Target Name: RECQL5
NCBI ID: G9400
Review Report on RECQL5 Target / Biomarker Content of Review Report on RECQL5 Target / Biomarker
RECQL5
Other Name(s): FLJ90603 | RECQL5 variant 3 | ATP-dependent DNA helicase Q5 (isoform 1) | RecQ helicase-like 5 | DNA helicase, RecQ-like type 5 | RECQ5 | RecQ5 | RECQL5 variant 1 | ATP-dependent DNA helicase Q5 (isoform 3) | RecQ5-beta | ATP-dependent DNA helicase Q5 | RecQ5-alpha | RecQ like helicase 5 | RecQ protein-like 5 | RECQ5_HUMAN

Exploring the Potential Applications of RECQL5 (FLJ90603) as a Drug Target or Biomarker

Abstract:
RecQL5 (FLJ90603) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker. Its unique structure and various functionalities make it an attractive candidate for further research in the field of drug development and personalized medicine. This article aims to provide an overview of the current understanding of RecQL5, its potential applications as a drug target or biomarker, and the ongoing research in this field.

Introduction:
RecQL5 (FLJ90603) is a non-coding RNA molecule that was identified as a potential drug target and biomarker. It is expressed in various tissues and cell types, including the brain, heart, and gastrointestinal tract, and has been shown to play important roles in various biological processes. One of the most promising aspects of RecQL5 is its potential as a drug target, as it has been shown to be involved in various cellular processes that are relevant to several diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. As a biomarker, RecQL5 has the potential to serve as a diagnostic tool for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

Current Understanding of RecQL5:
RecQL5 is a small non-coding RNA molecule that has a unique structure and function. It consists of 195 amino acid residues and has been shown to have various functionalities, including the ability to interact with various proteins, including transcription factors, and the ability to regulate gene expression. RecQL5 has also been shown to play important roles in various cellular processes, including cell growth, apoptosis, and inflammation.

RecQL5 has been shown to be involved in various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. For example, studies have shown that RecQL5 is involved in the regulation of cell apoptosis in various tissues, including the brain, and that it plays a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, studies have shown that RecQL5 is involved in the regulation of inflammation and that it has the potential to serve as a therapeutic target for various inflammatory diseases, including cancer and neurodegenerative diseases.

Potential Applications of RecQL5 as a Drug Target:
RecQL5's unique structure and various functionalities make it an attractive candidate for further research as a drug target. One of the most promising aspects of RecQL5 is its ability to interact with various proteins, including transcription factors, and the ability to regulate gene expression. These properties make it an attractive candidate for targeting various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases.

RecQL5 has been shown to play a role in the regulation of cell apoptosis, which is the process by which cells undergo programmed cell death. Studies have shown that RecQL5 is involved in the regulation of cell apoptosis in various tissues, including the brain, and that it plays a role in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. Additionally, studies have shown that RecQL5 is involved in the regulation of inflammation and that it has the potential to serve as a therapeutic target for various inflammatory diseases, including cancer and neurodegenerative diseases.

RecQL5 has also been shown to have a role in the regulation of angiogenesis, which is the process by which new blood vessels form in the body. This has potential implications for the development of new therapies for various diseases, including cancer and neurodegenerative diseases.

Potential Applications of RecQL5 as a Biomarker:
RecQL5 has also been shown to have potential as a biomarker for various diseases, including cancer, neurodegenerative diseases, and cardiovascular diseases. Its unique structure and various functionalities make it an attractive candidate for serving as a diagnostic tool

Protein Name: RecQ Like Helicase 5

Functions: DNA helicase that plays an important role in DNA replication, transcription and repair (PubMed:20643585, PubMed:22973052). Binds to the RNA polymerase II subunit POLR2A during transcription elongation and suppresses transcription-associated genomic instability (PubMed:20231364). Associates also with POLR1A and enforces the stability of ribosomal DNA arrays (PubMed:27502483). Plays an important role in mitotic chromosome separation after cross-over events and cell cycle progress (PubMed:22013166). Mechanistically, removes RAD51 filaments protecting stalled replication forks at common fragile sites and stimulates MUS81-EME1 endonuclease leading to mitotic DNA synthesis (PubMed:28575661). Required for efficient DNA repair, including repair of inter-strand cross-links (PubMed:23715498). Stimulates DNA decatenation mediated by TOP2A. Prevents sister chromatid exchange and homologous recombination

The "RECQL5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RECQL5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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