Understanding PPP6R2: A Potential Drug Target (G9701)

Target Name: PPP6R2

NCBI ID: G9701

PPP6R2

Understanding PPP6R2: A Potential Drug Target

PPP6R2 (Proteasome-Protein 6R2) is a protein that is expressed in various tissues of the human body. It is a key player in the proteasome system, which is responsible for breaking down and degrading proteins that are no longer needed. PPP6R2 has been identified as a potential drug target and has been shown to play a role in a variety of biological processes, including cancer, neurodegenerative diseases, and autoimmune disorders.

The Protein Proteasome

Proteasomes are complex structures that consist of a protein core and an electron microtic region that is responsible for the formation of new bonds between amino acids. They are a central component of the proteasome system, which is responsible for the efficient degradation of proteins that are no longer needed. PPP6R2 is a key player in this system, as it is a component of the protein core and is involved in the formation of new bonds between amino acids.

The Role of PPP6R2 in Proteasome Function

PPP6R2 is a key component of the proteasome system, as it is involved in the formation of the protein core. The formation of the protein core is a critical step in the proteasome system, as it allows for the formation of a stable and active structure that is capable of carrying out its function.

PPP6R2 is also involved in the regulation of the proteasome. Studies have shown that PPP6R2 can interact with the protein responsible for the regulation of the proteasome, known as the nuclear export protein (NEDP). This interaction between PPP6R2 and NEDP has been shown to play a role in the regulation of the proteasome and the degradation of proteins.

The Potential Role of PPP6R2 as a Drug Target

The potential use of PPP6R2 as a drug target is based on its involvement in a variety of biological processes, including cancer, neurodegenerative diseases, and autoimmune disorders. Studies have shown that PPP6R2 is involved in the development and progression of cancer, and that it may be a useful target for cancer therapies.

In addition, PPP6R2 has also been shown to be involved in the development and progression of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease. The potential use of PPP6R2 as a drug target for these conditions is an area of ongoing research and has the potential to lead to new treatments for these debilitating diseases.

PPP6R2 has also been shown to be involved in the regulation of the immune system, which is responsible for protecting the body against infection and disease. The potential use of PPP6R2 as a drug target for immune-related disorders is an area of ongoing research and has the potential to lead to new treatments for a variety of autoimmune disorders.

Conclusion

PPP6R2 is a protein that is expressed in various tissues of the human body and is involved in the proteasome system. It has been identified as a potential drug target due to its involvement in a variety of biological processes, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to fully understand the potential of PPP6R2 as a drug target and to develop effective treatments for these conditions.

Protein Name: Protein Phosphatase 6 Regulatory Subunit 2

Functions: Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

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