Target Name: PRDM8
NCBI ID: G56978
Review Report on PRDM8 Target / Biomarker Content of Review Report on PRDM8 Target / Biomarker
PRDM8
Other Name(s): KMT8D | PR domain zinc finger protein 8 | PR-domain containing protein 8 | PR/SET domain 8, transcript variant 2 | PR/SET domain 8, transcript variant 1 | PRDM8 variant 1 | EPM10 | PR domain-containing protein 8 | PRDM8 variant 2 | PRDM8_HUMAN | PR/SET domain 8 | PR domain containing 8 | PR domain 8 | PFM5

PRDM8: A Potential Drug Target for Cancer Treatment

PRDM8 (PR disease domain 8) is a gene that has been identified as a potential drug target or biomarker for the treatment of various diseases, including cancer. The gene is located on chromosome 6 and encodes a protein known as PRDM8.

PRDM8 is a key regulator of cell division and has been shown to play a role in the development and progression of various diseases, including cancer. The protein encoded by PRDM8 has been shown to promote the growth and division of cancer cells, and it is also involved in the regulation of cell death.

One of the key features of PRDM8 is its ability to interact with other genes and proteins. This interaction has been shown to play a role in the development and progression of various diseases, including cancer. For example, studies have shown that PRDM8 can interact with the protein PDGFR, which is involved in the development of many types of cancer.

Another key feature of PRDM8 is its ability to regulate the expression of other genes. This regulation has been shown to play a role in the development and progression of various diseases, including cancer. For example, studies have shown that PRDM8 can interact with the gene NF-kappa-B, which is involved in the regulation of inflammation and immune responses.

In addition to its role in the development and progression of diseases, PRDM8 is also a potential drug target. Studies have shown that PRDM8 can be targeted by small molecules, such as inhibitors, which can inhibit its interaction with other genes and proteins. This targeting has the potential to lead to the development of new treatments for various diseases, including cancer.

Overall, PRDM8 is a gene that has the potential to be a drug target or biomarker for the treatment of various diseases, including cancer. Further research is needed to fully understand its role and to develop effective treatments.

Protein Name: PR/SET Domain 8

Functions: Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3 (By similarity). Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR (By similarity). Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation (By similarity). In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival (By similarity)

The "PRDM8 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PRDM8 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRDM9 | PRDX1 | PRDX2 | PRDX2P4 | PRDX3 | PRDX4 | PRDX5 | PRDX6 | Pre-mRNA cleavage complex II | PREB | PRECSIT | Prefoldin complex | PRELID1 | PRELID1P6 | PRELID2 | PRELID3A | PRELID3B | PRELP | Prenyl diphosphate synthase | Prenyltransferase | PREP | PREPL | Presenilin | PREX1 | PREX2 | PRF1 | PRG1 | PRG2 | PRG3 | PRG4 | PRH1 | PRH1-PRR4 | PRH1-TAS2R14 | PRH2 | PRICKLE1 | PRICKLE2 | PRICKLE2-AS1 | PRICKLE2-AS2 | PRICKLE3 | PRICKLE4 | PRIM1 | PRIM2 | PRIM2BP | PRIMA1 | PRIMPOL | PRINS | PRKAA1 | PRKAA2 | PRKAB1 | PRKAB2 | PRKACA | PRKACB | PRKACG | PRKAG1 | PRKAG2 | PRKAG2-AS1 | PRKAG2-AS2 | PRKAG3 | PRKAR1A | PRKAR1B | PRKAR2A | PRKAR2A-AS1 | PRKAR2B | PRKCA | PRKCA-AS1 | PRKCB | PRKCD | PRKCE | PRKCG | PRKCH | PRKCI | PRKCQ | PRKCQ-AS1 | PRKCSH | PRKCZ | PRKCZ-AS1 | PRKD1 | PRKD2 | PRKD3 | PRKDC | PRKG1 | PRKG1-AS1 | PRKG2 | PRKG2-AS1 | PRKN | PRKRA | PRKRIP1 | PRKX | PRKXP1 | PRKY | PRL | PRLH | PRLHR | PRLR | PRM1 | PRM2 | PRM3 | PRMT1 | PRMT2 | PRMT3