Target Name: PREB
NCBI ID: G10113
Review Report on PREB Target / Biomarker Content of Review Report on PREB Target / Biomarker
PREB
Other Name(s): Prolactin regulatory element-binding protein | Prolactin regulatory element binding, transcript variant 1 | Mammalian guanine nucleotide exchange factor mSec12 | PREB variant 1 | prolactin regulatory element binding | Prolactin regulatory element-binding protein (isoform 1) | SEC12 | PREB_HUMAN | Prolactin regulatory binding-element protein | MGC3467 | mammalian guanine nucleotide exchange factor mSec12

A Promising Potential Drug Target:PREB

PREB is a novel protein that has been identified as a potential drug target in the medical field.PREB is a protein that is expressed in various tissues and cells in the body, including the brain, heart, and kidneys. It is involved in the regulation of cellular processes that are essential for the normal function of these organs, and it has been implicated in a number of diseases, including neurodegenerative disorders, cardiovascular disease, and kidney disease.

The Discovery of PREB

PREB was first identified through a combination of biochemical, cellular, and genetic studies. Researchers found that PREB was expressed in the brain and that it was involved in the regulation of neurotransmitter release and synaptic plasticity. They also found thatPREB was expressed in the kidneys and that it was involved in the regulation of kidney function. These findings suggested that PREB may have a role in the treatment of conditions that affect the brain and kidneys.

PREB's Potential Functions

PREB is involved in the regulation of a number of cellular processes that are essential for the normal function of the brain and kidneys. It is involved in the production and release of neurotransmitters, such as dopamine and GABA, which are critical for the normal function of the nervous system. It is also involved in the regulation of synaptic plasticity, which is the ability of the brain to change and adapt over time.

PREB is also involved in the regulation of cellular signaling pathways that are essential for the normal function of the brain and kidneys. It is involved in the production and activation of ion channels, which are responsible for the flow of electrical signals through the cell. It is also involved in the regulation of the levels of various signaling molecules, including neurotransmitters and hormones.

PREB's Role in Disease

PREB has been implicated in a number of diseases, including neurodegenerative disorders, cardiovascular disease, and kidney disease. It is involved in the regulation of the production and release of neurotransmitters, which are critical for the normal function of the nervous system. Therefore, disorders that affect the production or release of neurotransmitters, such as neurodegenerative disorders, may be treated by targeting PREB.

PREB is also involved in the regulation of cellular signaling pathways that are essential for the normal function of the brain and kidneys. Its involvement in these processes makes it a potential target for the development of new treatments for various diseases. For example, disorders that affect the regulation of ion channels, such as those that are involved in epilepsy, may be treated by targeting PREB.

PREB's Potential as a Drug Target

PREB is a promising potential drug target because it is involved in the regulation of cellular processes that are essential for the normal function of the brain and kidneys. Its involvement in the production and release of neurotransmitters, as well as its involvement in the regulation of cellular signaling pathways, makes it a potential target for the development of new treatments for a variety of diseases.

PREB is also a good candidate for a drug because it is expressed in a variety of tissues and cells in the body, which makes it more difficult to target. This makes it more difficult for enemies to attack it and more difficult for it to be expressed in unintended ways.

PREB's Potential Applications

PREB has the potential to be used

Protein Name: Prolactin Regulatory Element Binding

Functions: Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER

The "PREB Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PREB comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

PRECSIT | Prefoldin complex | PRELID1 | PRELID1P6 | PRELID2 | PRELID3A | PRELID3B | PRELP | Prenyl diphosphate synthase | Prenyltransferase | PREP | PREPL | Presenilin | PREX1 | PREX2 | PRF1 | PRG1 | PRG2 | PRG3 | PRG4 | PRH1 | PRH1-PRR4 | PRH1-TAS2R14 | PRH2 | PRICKLE1 | PRICKLE2 | PRICKLE2-AS1 | PRICKLE2-AS2 | PRICKLE3 | PRICKLE4 | PRIM1 | PRIM2 | PRIM2BP | PRIMA1 | PRIMPOL | PRINS | PRKAA1 | PRKAA2 | PRKAB1 | PRKAB2 | PRKACA | PRKACB | PRKACG | PRKAG1 | PRKAG2 | PRKAG2-AS1 | PRKAG2-AS2 | PRKAG3 | PRKAR1A | PRKAR1B | PRKAR2A | PRKAR2A-AS1 | PRKAR2B | PRKCA | PRKCA-AS1 | PRKCB | PRKCD | PRKCE | PRKCG | PRKCH | PRKCI | PRKCQ | PRKCQ-AS1 | PRKCSH | PRKCZ | PRKCZ-AS1 | PRKD1 | PRKD2 | PRKD3 | PRKDC | PRKG1 | PRKG1-AS1 | PRKG2 | PRKG2-AS1 | PRKN | PRKRA | PRKRIP1 | PRKX | PRKXP1 | PRKY | PRL | PRLH | PRLHR | PRLR | PRM1 | PRM2 | PRM3 | PRMT1 | PRMT2 | PRMT3 | PRMT5 | PRMT5-DT | PRMT6 | PRMT7 | PRMT8 | PRMT9 | PRNCR1 | PRND | PRNP | PRNT