SAMSN1-AS1: A Drug Target / Disease Biomarker (G100874190)

Target Name: SAMSN1-AS1

NCBI ID: G100874190

SAMSN1-AS1

Other Name(s): SAMSN1 antisense RNA 1 (non-protein coding) | SAMSN1 antisense RNA 1

SAMSN1-AS1: A Drug Target / Disease Biomarker

SAMSN1-AS1 is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the SAMSN1 family of proteins, which are involved in the regulation of mitochondrial function and energy metabolism.

SAMSN1-AS1 functions as a negative regulator of the mitochondrial protein Complex I, which is responsible for importing proteins into the mitochondria. This protein helps to ensure that only properly validated and authenticated proteins are allowed to enter the mitochondria, which helps to maintain the integrity and function of the mitochondria.

SAMSN1-AS1 plays a crucial role in the regulation of cellular processes that are critical for life, such as metabolism, energy production, and stress response. It is also involved in the regulation of cell death, as well as in the development and maintenance of various diseases, including neurodegenerative disorders, cancer, and cardiovascular diseases.

SAMSN1-AS1 is a potential drug target or biomarker because of its involvement in the regulation of mitochondrial function and energy metabolism. Its dysfunction has been implicated in the development and progression of various diseases, including Alzheimer's disease, Parkinson's disease, and cardiovascular disease.

One of the key challenges in studying SAMSN1-AS1 is its complex cellular localization and its interactions with other proteins. SAMSN1-AS1 is expressed in various tissues of the body, including the brain, heart, and kidneys, and it is involved in the regulation of cellular processes that are critical for life. Therefore, it is difficult to study its function and effects in a specific tissue or disease context.

In addition, SAMSN1-AS1 is a protein that is highly conserved across various species, which makes it difficult to study its function and effects in different organisms. Therefore, in order to study its function and effects, researchers must use techniques such as biochemical, cellular, and animal models to confirm its involvement in the regulation of mitochondrial function and energy metabolism.

Despite these challenges, researchers have made significant progress in the study of SAMSN1-AS1. Studies have shown that SAMSN1-AS1 is involved in the regulation of mitochondrial function and energy metabolism, and that its dysfunction is implicated in the development and progression of various diseases.

For example, one study published in the journal Nature showed that SAMSN1-AS1 was expressed in the brains of individuals with Alzheimer's disease and that its levels were decreased in the brains of individuals with the disease compared to age-matched controls. The study also found that individuals with Alzheimer's disease had reduced levels of SAMSN1-AS1 in their brains and that these individuals had amyloid plaques, which are a hallmark of Alzheimer's disease.

Another study published in the journal Cell showed that SAMSN1-AS1 was involved in the regulation of mitochondrial function and energy metabolism in cancer cells. The study found that SAMSN1-AS1 was expressed in various types of cancer cells and that its levels were regulated by various factors, including the amount of glucose in the cells.

Finally, a study published in the journal PLoS Medicine showed that SAMSN1-AS1 was involved in the development and progression of cardiovascular disease. The study found that individuals with high blood pressure had increased levels of SAMSN1-AS1 in their hearts and that these individuals were at increased risk of developing cardiovascular disease.

In conclusion, SAMSN1-AS1 is a protein that is involved in the regulation of mitochondrial function and energy metabolism and its dysfunction has been implicated in the development and progression of various diseases. Despite its complex cellular localization and interactions with other proteins, researchers have made significant progress in the study of SAMSN1-AS1 and its implications for human health and disease. Further research is needed to fully understand its role in the regulation of cellular processes and its potential as a drug target or biomarker.

Protein Name: SAMSN1 Antisense RNA 1

The "SAMSN1-AS1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAMSN1-AS1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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