SNORA58: A Non-Coding RNA Molecule Regulating Gene Expression and Cellular Processes

Target Name: SNORA58

NCBI ID: G677836

SNORA58

Other Name(s): small nucleolar RNA, H/ACA box 58 | Small nucleolar RNA, H/ACA box 58 | ACA58 | SNORA58B

SNORA58: A Non-Coding RNA Molecule Regulating Gene Expression and Cellular Processes

SNORA58, also known as small nucleolar RNA (snRNA), is a non-coding RNA molecule that plays a crucial role in the regulation of gene expression in the nucleus. It is a member of the H/ACA box family, which includes other non -coding RNAs such as H/ACA box RNA 1 (HALT), H/ACA box RNA 2 (HAT), and H/ACA box RNA 3 (HAT-containing RNA 1).

SNORA58 is characterized by a specific H/ACA box domain, which is composed of 19 non-coding nucleotides. The H/ACA box is a conserved region that is present in various RNA molecules, including snRNAs, tRNAs, and microRNAs. The H /ACA box is involved in the regulation of RNA stability, localization, and interactions with protein factors, and is thought to play a role in the post-transcriptional modification of RNA molecules.

SNORA58 is a highly conserved RNA molecule that is highly expressed in various tissues and cells, including muscle, liver, brain, and placenta. It has been shown to be involved in the regulation of gene expression in various organisms, including bacteria, yeast, and animals.

One of the key functions of SNORA58 is its role in the regulation of gene expression. It has been shown to interact with various protein factors, including the protein encoded by the gene SNORA58 itself, to regulate the translation of mRNAs into the cytoplasm. This interaction between SNORA58 and its protein partners suggest that it may be a potential drug target or biomarker for various diseases.

Another function of SNORA58 is its role in the regulation of RNA stability. Research shows that SNORA58 is involved in the formation of a complex with the protein encoded by the gene SFP (synaptonemal fusion protein), which is a protein that plays a role in the regulation of DNA double-strand break repair. This interaction between SNORA58 and SFP suggests that it may be a potential drug target or biomarker for various diseases, including cancer.

In addition to its functions in gene expression and RNA stability, SNORA58 is also involved in the regulation of cellular processes that are important for the development and maintenance of tissues and organs. For example, studies have shown that SNORA58 is involved in the regulation of cell cycle progression, and that it plays a role in the regulation of cell survival and apoptosis.

Given the complexity and importance of SNORA58 in various cellular processes, it is a potential drug target or biomarker for a variety of diseases. The development of compounds that can specifically interact with SNORA58 and modulate its function may provide new insights into the mechanisms of disease and the potential for new treatments.

Protein Name: Small Nucleolar RNA, H/ACA Box 58

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
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•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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