SNORA46: A Non-coding RNA Molecule Involved in DNA Replication and More

Target Name: SNORA46

NCBI ID: G677827

SNORA46

Other Name(s): small nucleolar RNA, H/ACA box 46 | ACA46 | Small nucleolar RNA, H/ACA box 46

SNORA46: A Non-coding RNA Molecule Involved in DNA Replication and More

SNORA46, also known as small nucleolar RNA (snRNA), is a non-coding RNA molecule that is primarily produced in the nucleolus of eukaryotic cells. It plays a critical role in the regulation of various cellular processes, including DNA replication, gene expression, and RNA metabolism. SNORA46 is a key player in the H/ACA box family of snRNAs, which are characterized by the presence of a specific hydrophobic domain in their sequence.

The H/ACA box is a conserved region that is found in the middle of many snRNAs. It is involved in the formation of RNA structures that are important for various cellular processes. The H/ACA box is also known for its ability to interact with other non-coding RNAs, such as histone modifications and histone-associated proteins.

SNORA46 is a 24nt RNA molecule that is primarily produced in the nucleolus of eukaryotic cells. It is one of several snRNAs that belong to the H/ACA box family. The H/ACA box is a conserved region that is found in the middle of many snRNAs. It is involved in the formation of RNA structures that are important for various cellular processes.

SNORA46 is expressed in a variety of tissues and cells, including the brain, heart, and testes. It is also highly expressed in the nucleolus, which is the site of DNA replication and gene expression in eukaryotic cells. This suggests that SNORA46 may be involved in the regulation of these processes.

One of the key functions of SNORA46 is its role in the regulation of DNA replication. DNA replication is a critical process for the growth and development of eukaryotic cells. It is during DNA replication that SNORA46 is thought to interact with the DNA replication machinery, helping to ensure accurate and efficient replication of the cell's genetic material.

In addition to its role in DNA replication, SNORA46 is also involved in the regulation of gene expression. It has been shown to interact with the RNA polymerase II (RNA polymerase II) complex, which is responsible for transcribing DNA into RNA. This suggests that SNORA46 may be involved in the regulation of gene expression by RNA polymerase II.

SNORA46 has also been shown to play a role in the regulation of RNA metabolism. It has been shown to interact with the protein known as UCS2, which is involved in the degradation of RNA. This suggests that SNORA46 may be involved in the regulation of the stability and stability of RNA molecules.

Furthermore, SNORA46 is also involved in the regulation of cellular signaling pathways. It has been shown to interact with the protein known as NF-YB, which is involved in the regulation of cellular signaling pathways. This suggests that SNORA46 may be involved in the regulation of cellular signaling pathways.

In conclusion, SNORA46 is a non-coding RNA molecule that is primarily produced in the nucleolus of eukaryotic cells. It is a key player in the H/ACA box family of snRNAs and is involved in the regulation of various cellular processes, including DNA replication, gene expression, and RNA metabolism. As a potential drug target or biomarker, SNORA46 is a promising target for future research.

Protein Name: Small Nucleolar RNA, H/ACA Box 46

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