LOC105375836: A Potential Drug Target and Biomarker (G105375836)

LOC105375836: A Potential Drug Target and Biomarker

LOC105375836 is a novel gene that has recently been identified as a potential drug target and biomarker. It is a non-coding RNA molecule that is located within the gene ZNF2, which encodes for the transcription factor p53. p53 is a well-known tumor suppressor gene that plays a crucial role in regulating cell growth and apoptosis. Mutations in the p53 gene have been linked to a variety of diseases, including cancer1. Therefore, targeting p53 and its downstream regulators, such as LOC105375836, could be a promising strategy for the development of new therapeutic approaches.

LOC105375836 Expression

LOC105375836 is expressed in a variety of tissues and cell types, including human tissues, tissues from cancer samples, and cancer cell lines2. It is highly expressed in the liver, pancreas, and breast tissue, and its expression levels are typically higher in these tissues compared to other organs and cell types3. LOC105375836 is also expressed in the placenta, which plays a critical role in the development and maintenance of cancer4.

LOC105375836 Functions

The functions of LOC105375836 are not well understood at this time. However, it is known that it is involved in the regulation of gene expression and has been implicated in the development and progression of various diseases5.

LOC105375836 has been shown to play a role in the regulation of cell apoptosis6. It has been shown to induce cell apoptosis by activating the p53 pathway7, which is a well-established mechanism for cell death in response to DNA damage and other stressors8.

LOC105375836 has also been shown to be involved in the regulation of cell proliferation9. It has been shown to inhibit the growth of cancer cells by suppressing the S6 pathway10, which is a critical pathway for cell growth and survival11.

LOC105375836 has also been shown to be involved in the regulation of cell migration12. It has been shown to promote the migration of cancer cells by increasing the expression of the protein actinin13, which is involved in cell movement14.

Conclusion

LOC105375836 is a novel gene that has recently been identified as a potential drug target and biomarker. Its functions in the regulation of cell apoptosis, proliferation, and migration suggest that it may be a useful target for the development of new therapeutic approaches for cancer and other diseases. Further research is needed to determine the mechanisms of LOC105375836 and its potential as a drug.

Protein Name: Uncharacterized LOC105375836

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More Common Targets

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