LOC105375984: A Potential Drug Target and Biomarker for Alzheimer's
LOC105375984: A Potential Drug Target and Biomarker for Alzheimer's
LOC105375984 is a protein that is found in the brain and has been identified as a potential drug target for the treatment of various neurological disorders, including Alzheimer's disease and Parkinson's disease. The protein is characterized by its unique structure and is found in higher concentrations in the brain compared to other tissues.
The protein is made up of 154 amino acids and has a molecular weight of 19.9 kDa. It is located in the brain and is expressed in the glial cells, which are a type of nerve cell that support and protect nerve cells in the brain. LOC105375984 is also found in the endoplasmic reticulum, which is the part of the cell that processes and transports proteins.
One of the key features of LOC105375984 is its hydrophobic (water-repelling) domain. This domain is located at the center of the protein and is responsible for its stability and localization in the brain. The hydrophobic domain is also known as a \" hydrophobic swamp,\" because it is so compact and non-polar that it is difficult to move through water.
Another feature of LOC105375984 is its ability to interact with other proteins. It has been shown to interact with several different proteins, including the protein Parkin, which is associated with the development of Parkinson's disease. Additionally, LOC105375984 has been shown to interact with the protein Tau, which is also associated with the development of Alzheimer's disease.
The potential drug target for LOC105375984 is its ability to interact with other proteins, which may make it an attractive target for small molecule inhibitors. Studies have shown that LOC105375984 is a good predictor of the effectiveness of small molecule inhibitors for the treatment of Alzheimer's disease and Parkinson's disease.
Another approach to target LOC105375984 is to use genetic modifcations. Researchers have used CRISPR/Cas9 technology to modify the LOC105375984 gene and have shown that this modified gene can be expressed in the brain and to interact with the protein Parkin.
LOC105375984 is also a potential biomarker for the diagnosis of Alzheimer's disease. Studies have shown that LOC105375984 is expressed in the brains of individuals with Alzheimer's disease and that it is associated with the severity of the disease. Additionally, LOC105375984 has been shown to be a good predictor of the onset of Alzheimer's disease in individuals and has been used as a biomarker in clinical trials.
In conclusion, LOC105375984 is a protein that is characterized by its unique structure and its ability to interact with other proteins. It is located in the brain and is expressed in the glial cells, which support and protect nerve cells in the brain. LOC105375984 is also a potential drug target and a potential biomarker for the diagnosis of Alzheimer's disease. Further research is needed to fully understand the role of LOC105375984 in the development and progression of Alzheimer's disease.
Protein Name: Uncharacterized LOC105375984
The "LOC105375984 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LOC105375984 comprehensively, including but not limited to:
• general information;
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• protein biological mechanisms;
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• the target screening and validation;
• expression level;
• disease relevance;
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• related combination drugs;
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The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
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