BATF: A protein involved in brain signaling and anxiety/depression

Target Name: BATF

NCBI ID: G10538

BATF

BATF: A protein involved in brain signaling and anxiety/depression

BATF (BATF-HUMAN) is a protein that is expressed in the human brain and is known for its role in the regulation of anxiety and depression. It is made by the brain and is found in the bloodstream, which makes it an attractive target for drug development.

BATF is a transmembrane protein that is involved in the regulation of various signaling pathways in the brain. It is a key regulator of the neurotransmitter systems, including dopamine and serotonin, which are involved in mood and anxiety. It is also involved in the regulation of ion channels and other signaling pathways that are important for the function of neurons.

BATF is a protein that is expressed in the brain and is involved in the regulation of various signaling pathways in the brain. It is a key regulator of the neurotransmitter systems, including dopamine and serotonin, which are involved in mood and anxiety. It is also involved in the regulation of ion channels and other signaling pathways that are important for the function of neurons.

One of the key functions of BATF is its role in the regulation of anxiety and depression. Studies have shown that BATF is involved in the regulation of the release of neurotransmitters, such as dopamine and serotonin, which are involved in mood and anxiety. BATF is also involved in the regulation of the function of neurons, which is important for the development and maintenance of anxiety and depression.

In addition to its role in the regulation of neurotransmitters, BATF is also involved in the regulation of ion channels and other signaling pathways that are important for the function of neurons. Studies have shown that BATF is involved in the regulation of the flow of ions through channels in the brain, which is important for the function of neurons.

Despite the potential benefits of BATF as a drug target, there are also concerns about its potential drawbacks. For example, because BATF is expressed in the brain, it is possible that any drugs that target it could have potential side effects on other parts of the brain. Additionally, because BATF is involved in the regulation of many different signaling pathways, it is possible that drugs that target it could have a wide range of effects on the body.

Overall, BATF is a protein that is expressed in the human brain and is involved in the regulation of various signaling pathways in the brain. It is a potential drug target due to its involvement in the regulation of anxiety and depression, as well as its role in the regulation of neurotransmitters and ion channels. Further research is needed to fully understand the potential benefits and risks of BATF as a drug target.

Protein Name: Basic Leucine Zipper ATF-like Transcription Factor

Functions: AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system: specifically mediates the differentiation of T-helper 17 cells (Th17), follicular T-helper cells (TfH), CD8(+) dendritic cells and class-switch recombination (CSR) in B-cells. Acts via the formation of a heterodimer with JUNB that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3'. The BATF-JUNB heterodimer also forms a complex with IRF4 (or IRF8) in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 (or IRF8) and activation of genes. Controls differentiation of T-helper cells producing interleukin-17 (Th17 cells) by binding to Th17-associated gene promoters: regulates expression of the transcription factor RORC itself and RORC target genes such as IL17 (IL17A or IL17B). Also involved in differentiation of follicular T-helper cells (TfH) by directing expression of BCL6 and MAF. In B-cells, involved in class-switch recombination (CSR) by controlling the expression of both AICDA and of germline transcripts of the intervening heavy-chain region and constant heavy-chain region (I(H)-C(H)). Following infection, can participate in CD8(+) dendritic cell differentiation via interaction with IRF4 and IRF8 to mediate cooperative gene activation. Regulates effector CD8(+) T-cell differentiation by regulating expression of SIRT1. Following DNA damage, part of a differentiation checkpoint that limits self-renewal of hematopoietic stem cells (HSCs): up-regulated by STAT3, leading to differentiation of HSCs, thereby restricting self-renewal of HSCs (By similarity)

The "BATF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about BATF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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