Target Name: LILRB3
NCBI ID: G11025
Review Report on LILRB3 Target / Biomarker Content of Review Report on LILRB3 Target / Biomarker
LILRB3
Other Name(s): leukocyte immunoglobulin like receptor B3 | LIR-3 | Leukocyte immunoglobulin like receptor B3, transcript variant 1 | monocyte inhibitory receptor HL9 | Leukocyte immunoglobulin-like receptor subfamily B member 3 | leucocyte Ig-like receptor B3 | leukocyte immunoglobulin-like receptor subfamily B member 4-like | CD85a antigen | ILT-5 | Monocyte inhibitory receptor HL9 | LILRB3 variant 1 | CD85 antigen-like family member A | CD85a | leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6 | ILT5 | leukocyte immunoglobulin-like receptor subfamily B member 3-like | PIR-B | Immunoglobulin-like transcript 5 | Leukocyte immunoglobulin-like receptor 3 | MGC138403 | immunoglobulin-like transcript 5 | CD85A | PIRB | LILRA6 | LIRB3_HUMAN | Leukocyte immunoglobulin-like receptor subfamily B member 3 isoform 1 precursor (isoform 1) | leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3 | HL9 | LIR3

Regulation of Immune System and Cancer Progression By LILRB3

Leukocyte immunoglobulin-like receptor B3 (LILRB3) is a protein that is expressed in various tissues throughout the body, including the immune system, skin, and hair. It is a member of the immunoglobulin superfamily and is responsible for regulating the movement of immune cells into the site of inflammation. LILRB3 has also been shown to play a role in cancer progression and has potential as a drug target or biomarker.

Disease Progression

LILRB3 is a well-established player in the immune system and has been involved in the regulation of a wide range of immune responses. One of its most well-documented functions is its role in the regulation of T cell development and activation. LILRB3 has been shown to play a critical role in the development of CD4+ T cells, which are a crucial part of the immune system and are responsible for protecting the body against a wide range of pathogens.

In addition to its role in T cell development, LILRB3 has also been shown to play a critical role in the regulation of immune cell function. For example, LILRB3 has been shown to regulate the movement of immune cells into the site of inflammation, which is important for ensuring that immune cells are able to effectively respond to an infection or injury.

Drug Target Potential

The potential drug target for LILRB3 is based on its role in the regulation of immune cell function and its involvement in the development of cancer. Several studies have shown that LILRB3 is involved in the regulation of cancer cell growth and progression, and that inhibiting its activity may be an effective way to treat cancer.

One of the key challenges in targeting LILRB3 as a drug is its widespread distribution in the body. LILRB3 is expressed in a wide range of tissues and cells, including immune cells, muscle cells, and epithelial cells. This makes it difficult to predict where and how LILRB3 would be expressed in a given tissue, and to design an effective drug that specifically targets it.

Another challenge is the potential complexity of LILRB3's role in the immune system. LILRB3 is involved in the regulation of a wide range of immune cell functions, and it is not clear exactly how the activity of LILRB3 contributes to the immune response. This makes it difficult to design a drug that effectively inhibits its activity and achieves the desired therapeutic effect.

Biomarker Potential

In addition to its potential as a drug target, LILRB3 has also been shown to have potential as a biomarker. The expression of LILRB3 has been shown to be associated with a number of diseases, including cancer, autoimmune disorders, and skin diseases. This makes LILRB3 an attractive candidate as a biomarker for a variety of diseases.

One of the key challenges in using LILRB3 as a biomarker is its limited expression in certain tissues. LILRB3 is expressed in most tissues of the body, but it is not expressed in certain tissues, such as the brain or the liver. This makes it difficult to use LILRB3 as a reliable biomarker for a wide range of diseases.

Another challenge is the complexity of LILRB3's role in the immune system. LILRB3 is involved in the regulation of a wide range of immune cell functions, and it is not clear exactly how the activity of LILRB3 contributes to the immune response. This makes it difficult to use LILRB3 as a reliable biomarker for the immune system.

Conclusion

In conclusion, LILRB3 is a protein that is widely expressed in various tissues throughout the body and is involved in the regulation of the immune system. Its potential as a drug target or biomarker is based on its role in the regulation of immune cell function and its involvement in the development of cancer. Further research is needed to fully understand the activity of LILRB3 and its potential as a therapeutic agent.

Protein Name: Leukocyte Immunoglobulin Like Receptor B3

The "LILRB3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LILRB3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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LILRB4 | LILRB5 | LILRP1 | LILRP2 | LIM domain kinase (LIMK) | LIM2 | LIMA1 | LIMASI | LIMCH1 | LIMD1 | LIMD1-AS1 | LIMD2 | LIME1 | LIMK1 | LIMK2 | LIMS1 | LIMS2 | LIMS3 | LIMS3-LOC440895 | LIMS4 | LIN28A | LIN28B | LIN28B-AS1 | LIN37 | LIN52 | LIN54 | LIN7A | LIN7B | LIN7C | LIN9 | LINC-PINT | LINC-ROR | LINC00028 | LINC00029 | LINC00032 | LINC00051 | LINC00052 | LINC00092 | LINC00102 | LINC00106 | LINC00111 | LINC00112 | LINC00113 | LINC00114 | LINC00115 | LINC00158 | LINC00159 | LINC00160 | LINC00161 | LINC00163 | LINC00173 | LINC00174 | LINC00184 | LINC00189 | LINC00200 | LINC00205 | LINC00207 | LINC00208 | LINC00210 | LINC00221 | LINC00222 | LINC00226 | LINC00235 | LINC00239 | LINC00240 | LINC00242 | LINC00243 | LINC00244 | LINC00251 | LINC00260 | LINC00261 | LINC00265 | LINC00266-1 | LINC00266-3 | LINC00272 | LINC00273 | LINC00276 | LINC00278 | LINC00293 | LINC00294 | LINC00298 | LINC00299 | LINC00301 | LINC00303 | LINC00304 | LINC00305 | LINC00308 | LINC00309 | LINC00310 | LINC00311 | LINC00312 | LINC00313 | LINC00314 | LINC00316 | LINC00317 | LINC00319 | LINC00320 | LINC00323 | LINC00324 | LINC00326