ADSS1: Enzyme Involved in Adenosine Synthesis (G122622)

Target Name: ADSS1

NCBI ID: G122622

ADSS1

ADSS1: Enzyme Involved in Adenosine Synthesis

Adenylosuccinate synthetase isozyme 1 (ISOform 1), also known as ADSS1, is an enzyme involved in the synthesis of adenosine, a molecule that plays a crucial role in various physiological processes in the body. The ability of ADSS1 to convert farnesine, a low-energy molecule found in all living cells, into adenosine provides the energy source for the catalytic cycle, which is the central energy-producing process of eukaryotic cells. In addition to its role in energy metabolism, ADSS1 is also involved in the regulation of cellular signaling pathways and is a potential drug target in the treatment of various diseases.

The synthesis of adenosine from farnesine via the ADSS1 enzyme is a critical step in the biosynthesis pathway of this molecule. Farnesine is a crucial precursor for the synthesis of adenosine, as it provides the carbon and nitrogen atoms necessary for the construction of the adenine ring. The biosynthesis of adenosine from farnesine via ADSS1 is a highly regulated process that involves multiple enzymes and a series of steps, including the conversion of farnesine to its active form, the addition of a phosphate group, and the formation of the adenylosuccinyl-enzyme intermediate.

ADSS1 is a member of the superfamily of nucleotideases, which are enzymes that catalyze the hydrolysis of nucleotides to nucleotides. These enzymes are responsible for the rapid and efficient breakdown of nucleotides, which is critical for the synthesis of new nucleotides and the regulation of various cellular processes. The highly specificity of ADSS1 for the synthesis of adenosine from farnesine indicates that this enzyme plays a critical role in the regulation of adenosine levels and function in various cellular processes.

The role of ADSS1 in cellular signaling pathways is another potential drug target for this enzyme. ADSS1 is involved in the regulation of various signaling pathways, including the signaling pathways that are responsible for cell growth, differentiation, and survival. In addition to its role in the regulation of signaling pathways, ADSS1 is also involved in the regulation of cellular metabolism and is a potential target for drugs that are designed to disrupt cellular processes that are necessary for the survival and growth of cancer cells.

The potential drug targets for ADSS1 are numerous and varied. One of the most promising targets for this enzyme is the treatment of cancer. ADSS1 has been shown to play a critical role in the regulation of various cellular processes that are necessary for cancer cell growth, including the regulation of cell growth, apoptosis, and angiogenesis. Therefore, inhibitors of ADSS1 have been shown to be effective in the treatment of various types of cancer, including breast, ovarian, and prostate cancers.

In addition to its potential as a cancer therapeutic, ADSS1 has also been shown to have potential as a treat for other diseases. For example, the levels of ADSS1 have been shown to be elevated in individuals with heart disease, which may indicate that this enzyme plays a role in the regulation of cardiovascular function. Additionally, ADSS1 has also been shown to be involved in the regulation of cellular signaling pathways, which may indicate that it plays a role in the regulation of various diseases.

The structure and function of ADSS1 are also of interest as potential drug targets. The structure of ADSS1 is highly conserved across various species, which suggests that it plays a role in the basic biochemical processes that are necessary for life. The unique function of ADSS1, as the enzyme involved in the synthesis of adenosine from farnesine, also suggests that this enzyme plays a critical role in the regulation of various cellular processes.

In conclusion, ADSS1 is an enzyme involved in the synthesis of adenosine from farnesine and has been shown to play a critical role in various cellular processes

Protein Name: Adenylosuccinate Synthase 1

Functions: Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP

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•   protein biological mechanisms;
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