Target Name: AGMAT
NCBI ID: G79814
Review Report on AGMAT Target / Biomarker Content of Review Report on AGMAT Target / Biomarker
AGMAT
Other Name(s): agmatinase | SPEB_HUMAN | Agmatine ureohydrolase | agmatine ureohydrolase (agmatinase) | Agmatinase | Agmatinase, mitochondrial | AUH

AGMAT: A Novel Enzyme with Potential as A Drug Target Or Biomarker

AGMAT (Agmatinase), a novel enzyme discovered in the late 1990s, has the potential to be a drug target or biomarker for various diseases, including diabetes, cardiovascular disease, and neurodegenerative disorders. Its unique catalytic mechanism, which involves the conversion of agmatin into its active form, has been the subject of intense research in recent years, and has led to a greater understanding of its biological function and potential applications.

AGMAT (Agmatinase) is an enzyme that catalyzes the conversion of agmatin into its active form, which is highly reactive and has been shown to have a wide range of physiological functions. This enzyme is found in various organisms, including bacteria, archaea, and eukaryotes , and has been shown to be involved in a variety of cellular processes, including inflammation, stress response, and metabolism.

One of the unique features of AGMAT is its catalytic mechanism, which involves a specific intermediate step that converts agmatin into its active form. This intermediate step is formed by the addition of a side chain to agmatin, which creates a new compound that is then hydrolyzed to produce the active form. This catalytic mechanism allows AGMAT to convert agmatin into its active form with high efficiency and selectivity, and is the basis for its unique catalytic properties.

AGMAT has been shown to have a wide range of physiological functions, including the regulation of inflammation, stress response, and metabolism. For example, AGMAT has been shown to play a key role in the regulation of inflammation, with studies showing that it has anti -inflammatory effects and is involved in the production of pro-inflammatory cytokines. Additionally, AGMAT has been shown to be involved in the regulation of stress response, with studies showing that it is involved in the production of stress hormones and has anti-stress effects . Finally, AGMAT has also been shown to be involved in metabolism, with studies showing that it is involved in the metabolism of a variety of molecules, including nutrients and toxins.

AGMAT's potential as a drug target or biomarker has led to a great deal of interest in recent years, with several studies showing that it has the potential to be a useful therapeutic agent for a variety of diseases. For example, AGMAT has been shown to have potential as a treatment for diabetes, with studies showing that it has low toxicity and can effectively lower blood sugar levels in diabetic rats. Additionally, AGMAT has also been shown to have potential as a treatment for cardiovascular disease, with studies showing that it has anti -inflammatory effects and can improve blood flow in cardiovascular-edge devices.

AGMAT has also been shown to have potential as a biomarker for a variety of diseases, including neurodegenerative disorders. For example, AGMAT has been shown to be involved in the development of neurodegenerative disorders, with studies showing that it is involved in the aggregation of beta -amyloid peptides and can contribute to the development of neurodegeneration. Additionally, AGMAT has also been shown to be involved in the development of other diseases, including cancer and liver disease.

In conclusion, AGMAT is a novel enzyme that has the potential to be a drug target or biomarker for a variety of diseases. Its unique catalytic mechanism and wide range of physiological functions make it an attractive candidate for further research and potential therapeutic applications. Further studies are needed to fully understand AGMAT's role in biology and its potential as a therapeutic agent.

Protein Name: Agmatinase

The "AGMAT Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AGMAT comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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