Target Name: CS
NCBI ID: G1431
Review Report on CS Target / Biomarker Content of Review Report on CS Target / Biomarker
CS
Other Name(s): Citrate synthase | citrate synthase | CISY_HUMAN | citrate (Si)-synthase | Citrate (Si)-synthase | Citrate synthase, mitochondrial

CS: An Attractive Drug Target for Aromatic Amino Acid Biosynthesis

Citrate synthase (CS) is a enzyme that plays a critical role in the biosynthesis of aromatic amino acids, which are important molecules found in a variety of organisms, including humans. Aromatic amino acids are the building blocks of life and are involved in many important cellular processes, including DNA replication, gene regulation, and signaling pathways.

CS is a protein that is expressed in many different tissues and cells in the body. It is found in the cytoplasm of eukaryotic cells and is responsible for catalyzing the conversion of tryptophan, a key aromatic amino acid, to indole-3-pyruvate. This conversion is a critical step in the biosynthesis of aromatic amino acids and is essential for the survival of the organism.

CS is a enzyme that is involved in many different cellular processes in the body. It is found in the cytoplasm of eukaryotic cells and is responsible for catalyzing the conversion of tryptophan, a key aromatic amino acid, to indole-3-pyruvate. This conversion is a critical step in the biosynthesis of aromatic amino acids and is essential for the survival of the organism.

One of the things that makes CS an attractive drug target is its location in the cytoplasm. As mentioned earlier, CS is found in the cytoplasm of eukaryotic cells, which makes it a difficult target to reach. However, there are currently several drugs that are being developed to target CS, including some that are designed to inhibit the activity of CS.

Another reason why CS is an attractive drug target is its role in the biosynthesis of aromatic amino acids. As mentioned earlier, aromatic amino acids are the building blocks of life and are involved in many important cellular processes. Therefore, any drug that can inhibit the activity of CS and prevent the biosynthesis of aromatic amino acids could be a valuable drug.

In addition to its role in the biosynthesis of aromatic amino acids, CS is also involved in many other cellular processes in the body. For example, CS is involved in the metabolism of many different molecules, including nucleotides, lipids, and proteins. It is also involved in the regulation of many different cellular processes, including cell growth, differentiation, and apoptosis.

Overall, CS is a protein that is involved in many different cellular processes in the body. Its location in the cytoplasm makes it a difficult target, but there are currently several drugs that are being developed to target CS. Its role in the biosynthesis of aromatic amino acids, as well as its involvement in many other cellular processes, make it an attractive drug target.

Protein Name: Citrate Synthase

The "CS Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about CS comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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