Unraveling the Potential Applications of FAM218A: A Characterized Uncharacterized Protein C4orf39

Target Name: FAM218A

NCBI ID: G152756

FAM218A

Unraveling the Potential Applications of FAM218A: A Characterized Uncharacterized Protein C4orf39

Introduction

Protein C4orf39, also known as FAM218A, is a highly conserved protein that is expressed in various cell types of the human body. It is a part of the same superfamily as the protein CFP10, which is known to play a crucial role in intracellular signaling. The discovery of protein C4orf39 has raised significant interest in its potential applications as a drug target or biomarker. In this article, we will delve into the molecular structure, function, and potential applications of protein C4orf39.

Molecular Structure and Localization

Protein C4orf39 is a 163-amino acid protein with a calculated molecular mass of 21.9 kDa. It is expressed in various tissues and cells of the human body, including the brain, heart, liver, and gastrointestinal tract. Protein C4orf39 is predominantly localized to the endoplasmic reticulum (ER), a protein-rich organ that plays a crucial role in the delivery and processing of proteins from the cytoplasm to the cell surface.

Function and Potential Applications

The function of protein C4orf39 is not well understood, but its conserved amino acid sequence suggests that it may be involved in intracellular signaling pathways. Several studies have demonstrated that protein C4orf39 is involved in various cellular processes, including cell adhesion, migration, and survival.

One of the most promising applications of protein C4orf39 is its potential as a drug target. The kinase-like domain (KD) of protein C4orf39 is known to play a crucial role in the regulation of protein kinase activity, thereby modulating various cellular processes. Several studies have shown that inhibition of protein C4orf39 KD can lead to the inhibition of protein kinase activity, resulting in the inhibition of cellular processes that are associated with cancer growth and progression. This suggests that protein C4orf39 KD may be an attractive target for cancer therapy.

Another potential application of protein C4orf39 is its role as a biomarker for various diseases, including neurodegenerative disorders and chronic diseases. The conserved nature of protein C4orf39 across various species suggests that it may be a useful protein for the development of biomarkers that can be used to diagnose and monitor diseases.

Conclusion

In conclusion, protein C4orf39 is a highly conserved protein that is expressed in various cell types of the human body. Its function and potential applications are still being explored, but its conserved amino acid sequence and kinase-like domain suggest that it may be involved in intracellular signaling pathways and may be an attractive target for drug development and biomarker development. Further research is needed to fully understand the role of protein C4orf39 in various cellular processes and to determine its potential as a drug target or biomarker.

Protein Name: Family With Sequence Similarity 218 Member A

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