Target Name: FAM229A
NCBI ID: G100128071
Review Report on FAM229A Target / Biomarker Content of Review Report on FAM229A Target / Biomarker
Other Name(s): hypothetical protein LOC100128071 | Protein FAM229A | similar to hCG41624 | F229A_HUMAN | Family with sequence similarity 229 member A | family with sequence similarity 229 member A | LOC100128071

What is FAM229A?

FAM229A, also known as Family with sequence similarity 229 member A, is a novel protein that has recently emerged as a potential drug target and biomarker. This article aims to delve into the various aspects of FAM229A, including its function, role in disease development, and its potential as a therapeutic target or biomarker.

FAM229A Function and Molecular Characteristics

FAM229A is a relatively unknown protein with limited information available about its precise function. It is encoded by the FAM229A gene, located on chromosome 17 in humans. The FAM229A protein consists of 222 amino acids and participates in various biological processes, although its exact mechanism of action remains elusive. Further research is necessary to gain a comprehensive understanding of FAM229A function.

FAM229A and Disease Development

Despite limited knowledge about FAM229A, recent studies have shown its potential involvement in certain disease processes. One study conducted on a small cohort of patients indicated that FAM229A expression levels were significantly elevated in individuals with pancreatic cancer (PC), suggesting its association with PC development. This finding has opened avenues for investigating FAM229A as a potential biomarker for early detection or monitoring of PC.

Additionally, FAM229A has also been implicated in other malignancies. In breast cancer, its overexpression has been observed, and further studies are underway to determine its significance as a prognostic biomarker and potential therapeutic target. Furthermore, several bioinformatics analyses have identified potential interactions between FAM229A and various genes involved in cancer pathways, highlighting its possible role in tumorigenesis and progression.

FAM229A as a Drug Target

The identification of novel drug targets is vital for the development of effective therapeutic strategies against diseases. The emerging evidence suggesting the involvement of FAM229A in cancer development has sparked interest in exploring its potential as a druggable target.

Several approaches can be taken to target FAM229A. One possibility is to develop small molecule inhibitors that can specifically bind to FAM229A, disrupting its function and inhibiting disease progression. The identification of the precise binding sites within the protein structure is crucial for the design and development of effective inhibitors. However, further research is needed to fully understand the structure and function of FAM229A.

Another approach to target FAM229A is through the use of gene therapy. The development of gene-based therapies, such as siRNA or antisense oligonucleotides, could provide a means to specifically downregulate FAM229A expression, potentially halting disease progression. However, these approaches have their limitations and require further refinement and optimization before clinical application.

Potential as a Biomarker

Biomarkers play a crucial role in disease diagnosis, prognosis, and treatment monitoring. The expression levels of FAM229A have shown promise as a potential biomarker in various diseases, particularly cancer.

In pancreatic cancer, the elevated expression of FAM229A in patient samples suggest its potential as a diagnostic biomarker. Early detection of PC is challenging due to the lack of specific symptoms and reliable screening methods. FAM229A could serve as a valuable tool in PC screening, potentially enabling earlier diagnosis and improved patient outcomes.

Additionally, FAM229A expression levels may hold prognostic value in various malignancies. Studies have shown that higher expression levels of FAM229A correlate with poorer prognosis in breast cancer patients. Monitoring FAM229A levels during treatment could provide valuable information on disease progression and treatment efficacy.


FAM229A is a promising protein that has recently gained attention as a potential drug target and biomarker. Although its precise function and molecular mechanism remain largely unknown, emerging evidence suggests its involvement in various disease processes, particularly cancer.

Further research is necessary to unveil the precise function of FAM229A and its potential involvement in different biological pathways. Understanding the molecular details of FAM229A could aid in the development of targeted therapies and the utilization of FAM229A as a reliable biomarker for disease diagnosis, prognosis, and treatment response assessment. Continued exploration of FAM229A could potentially lead to improved patient outcomes and personalized medicine approaches in the future.

Protein Name: Family With Sequence Similarity 229 Member A

The "FAM229A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM229A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at

More Common Targets

FAM229B | FAM230B | FAM230F | FAM230H | FAM230I | FAM230J | FAM234A | FAM234B | FAM237A | FAM237B | FAM238B | FAM238C | FAM239B | FAM240C | FAM241A | FAM241B | FAM242A | FAM245A | FAM24A | FAM24B | FAM25A | FAM25BP | FAM25C | FAM25G | FAM27B | FAM27E2 | FAM27E3 | FAM27E4 | FAM27E5 | FAM30A | FAM32A | FAM32BP | FAM3A | FAM3B | FAM3C | FAM3D | FAM3D-AS1 | FAM41AY1 | FAM41C | FAM43A | FAM43B | FAM47A | FAM47B | FAM47C | FAM47E | FAM47E-STBD1 | FAM50A | FAM50B | FAM53A | FAM53B | FAM53C | FAM66A | FAM66B | FAM66C | FAM66D | FAM66E | FAM72A | FAM72B | FAM72C | FAM72D | FAM74A1 | FAM74A3 | FAM74A4 | FAM76A | FAM76B | FAM78A | FAM78B | FAM81A | FAM81B | FAM83A | FAM83A-AS1 | FAM83B | FAM83C | FAM83C-AS1 | FAM83D | FAM83E | FAM83F | FAM83G | FAM83H | FAM83H antisense RNA 1 (head to head) | FAM85A | FAM85B | FAM86B1 | FAM86B2 | FAM86B2-DT | FAM86B3P | FAM86C1P | FAM86C2P | FAM86DP | FAM86EP | FAM86FP | FAM86HP | FAM86JP | FAM86KP | FAM86MP | FAM87A | FAM87B | FAM88C | FAM88D | FAM88E