Target Name: RNF217
NCBI ID: G154214
Review Report on RNF217 Target / Biomarker Content of Review Report on RNF217 Target / Biomarker
RNF217
Other Name(s): DJ84N20.1 | IBRDC1 | ring finger protein 217 | E3 ubiquitin-protein ligase RNF217 (isoform b) | OTTHUMP00000017132 | C6orf172 | E3 ubiquitin-protein ligase RNF217 (isoform a) | dJ84N20.1 | E3 ubiquitin-protein ligase RNF217 | MGC26996 | IBR domain containing 1 | Ring finger protein 217, transcript variant 2 | IBR domain-containing protein 1 | Probable E3 ubiquitin-protein ligase RNF217 | Opposite STL | RNF217 variant 2 | RING finger protein 217 | RNF217 variant 1 | OSTL | Ring finger protein 217, transcript variant 1 | opposite STL | RN217_HUMAN | probable E3 ubiquitin-protein ligase RNF217

RNA Fingerprint Technology: Drug Development & Disease Diagnosis

RNA-Nucleic Acid (RNA) fingerprinting is a technology that can quantitatively and qualitatively analyze RNA molecules. Since each person's RNA sequences are unique, they can be studied as potential drug targets or biomarkers. RNA fingerprinting technology has been widely used in drug development, disease diagnosis and treatment.

The basic principle of RNA fingerprinting technology is to amplify target RNA molecules through primers, and then sequence the amplified products to obtain their sequence information. This sequence information can be used to construct an RNA fingerprint library, a collection of known RNA sequences. Subsequently, by comparing the sequence of the RNA molecule to be tested with the sequences in the RNA fingerprint library, it can be determined which category the RNA molecule to be tested belongs to, so that further research can be conducted.

Application of RNA fingerprint technology in drug research and development
The role of RNA fingerprint technology in drug research and development is mainly to screen and identify drug targets. Due to the specificity of RNA molecules in drug reactions, drug targets can be detected quickly and accurately through RNA fingerprint technology, thereby narrowing the scope of drug development and improving drug development efficiency.

Take EGFR mutants as an example. The protein encoded by the EGFR gene is a common tumor suppressor protein, and its mutants have a high incidence in a variety of tumors. Therefore, researchers hope to screen EGFR mutants through RNA fingerprinting technology to screen out compounds with potential therapeutic effects.

Application of RNA fingerprint technology in disease diagnosis
The application of RNA fingerprint technology in disease diagnosis is mainly to analyze the expression of RNA molecules in tumor tissues to determine the type and extent of the tumor and provide a basis for further treatment of the tumor.

Take lung cancer as an example. Lung cancer is a common malignant tumor, and its treatment mainly relies on detecting the EGFR gene expression level in tumor tissue. Since the expression level of EGFR gene in lung cancer is affected by many factors, such as age, gender, tumor size, etc., RNA fingerprinting technology can be used to quantitatively analyze the expression level of EGFR gene in lung cancer tissue, thereby providing a basis for the diagnosis of lung cancer. Provide a more accurate basis for diagnosis and treatment.

Application of RNA fingerprint technology in drug monitoring
The application of RNA fingerprint technology in drug monitoring is mainly to monitor the expression of drugs in the body to determine whether the drug has achieved the expected therapeutic effect, or to detect whether adverse reactions occur during the treatment process.

Take Parkinson's disease as an example. Parkinson's disease is a common neurodegenerative disease whose symptoms mainly include muscle rigidity and decreased movement. At present, the treatment of Parkinson's disease mainly relies on drug therapy. By monitoring the expression of drugs in the body, it can be determined whether the drug has achieved the expected therapeutic effect, and whether adverse reactions occur during the treatment process, thereby providing information for Parkinson's disease. Provide more accurate basis for disease treatment.

Application of RNA fingerprint technology in drug development and disease diagnosis
RNA fingerprint technology is widely used in drug development and disease diagnosis. It can detect and analyze RNA molecules quickly and accurately, providing a more accurate basis for drug development and disease diagnosis. With the continuous development of RNA fingerprint technology, it will play a more important role in drug development and disease diagnosis, bringing good news to people's health.

Protein Name: Ring Finger Protein 217

Functions: E3 ubiquitin-protein ligase which accepts ubiquitin from E2 ubiquitin-conjugating enzymes in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Mediates the degradation of the iron exporter ferroportin/SLC40A1 and thus regulates iron homeostasis

The "RNF217 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about RNF217 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RNF217-AS1 | RNF220 | RNF222 | RNF224 | RNF225 | RNF227 | RNF24 | RNF25 | RNF26 | RNF31 | RNF32 | RNF32-DT | RNF34 | RNF38 | RNF39 | RNF4 | RNF40 | RNF41 | RNF43 | RNF44 | RNF5 | RNF5P1 | RNF6 | RNF7 | RNF7P1 | RNF8 | RNFT1 | RNFT2 | RNGTT | RNH1 | RNLS | RNMT | RNPC3 | RNPC3-DT | RNPEP | RNPEPL1 | RNPS1 | RNPS1P1 | RNR1 | RNR2 | RNU1-1 | RNU1-100P | RNU1-108P | RNU1-11P | RNU1-134P | RNU1-18P | RNU1-3 | RNU1-31P | RNU1-32P | RNU1-36P | RNU1-38P | RNU1-4 | RNU1-42P | RNU1-55P | RNU1-61P | RNU1-63P | RNU1-72P | RNU1-73P | RNU1-78P | RNU1-7P | RNU1-82P | RNU1-88P | RNU105B | RNU11 | RNU12 | RNU2-1 | RNU2-17P | RNU2-2P | RNU2-4P | RNU2-54P | RNU2-5P | RNU2-6P | RNU4-1 | RNU4-14P | RNU4-2 | RNU4-30P | RNU4-33P | RNU4-38P | RNU4-39P | RNU4-46P | RNU4-53P | RNU4-62P | RNU4-6P | RNU4-76P | RNU4-82P | RNU4-87P | RNU4-91P | RNU4-9P | RNU4ATAC | RNU4ATAC11P | RNU4ATAC18P | RNU5A-1 | RNU5A-4P | RNU5A-8P | RNU5B-1 | RNU5B-4P | RNU5D-1 | RNU5E-1 | RNU5E-6P | RNU5F-1