Liver Failure, Acute Infantile
Liver Failure, Acute Infantile
About the Disease
Liver Failure, Infantile, Transient, also known as acute infantile liver failure due to synthesis defect of mtdna-encoded proteins, is related to infantile liver failure syndrome and spinocerebellar ataxia, autosomal recessive 21, and has symptoms including icterus and vomiting. An important gene associated with Liver Failure, Infantile, Transient is TRMU (TRNA Mitochondrial 2-Thiouridylase), and among its related pathways/superpathways is tRNA-uridine 2-thiolation (mammalian mitochondria). Affiliated tissues include liver and skin, and related phenotypes are hepatomegaly and feeding difficulties in infancy
Common Targets
G60561 | G55687 | G9971 | G51520 | G51594
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Liver Failure, Acute Infantile, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
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