Myelodysplasia
About the Disease
Myelodysplastic Syndrome, also known as myelodysplastic syndromes, is related to leukemia, acute myeloid and juvenile myelomonocytic leukemia. An important gene associated with Myelodysplastic Syndrome is TET2 (Tet Methylcytosine Dioxygenase 2), and among its related pathways/superpathways is Embryonic and Induced Pluripotent Stem Cells and Lineage-specific Markers. The drugs Posaconazole and Micafungin have been mentioned in the context of this disorder. Affiliated tissues include Placenta and Umbilical Cord, and related phenotypes are myelodysplasia and neoplasm
Common Targets
G2885 | G930 | G3995 | G7422 | G23532 | G10497 | G327 | G54897 | G8938 | G9314 | G79072 | G254102 | G5347 | G3203 | G3232 | G114548 | CDK4/Cyclin D3 | G238 | G100126299 | G2782 | G2950 | G5777 | G3604 | G3718 | G3716 | G324 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | G11200 | G6647 | G4353 | G7525 | G847 | G1535 | G6654 | G3911 | G4102 | G596 | G4647 | G2339 | G6714 | G51185 | G5196 | G3791 | G7515 | G89766 | G3055 | G3233 | G4707 | G9578 | G3320 | DNA Methyltransferase (DNMT) (nonspecified subtype) | G4683 | G79919 | G3204 | G1576 | G6929 | G2073 | G2268 | G4194 | G6622 | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G8241 | G57817 | P5575 | G6790 | G2235 | G3234 | G55556 | P12956 | P16165 | G1956 | G79184 | G25 | G4967 | G3845 | G10769 | G10669 | G9833 | G3717 | G8651 | G3235 | G8854 | G149934 | G51230 | G10670 | G150290 | G129563 | G56243 | G401494 | G402381 | G201243 | G10347 | P26505 | G146395 | G3236 | G171023 | G6774 | G4437 | G4615 | G9353 | G57787 | G1660 | G10538 | G3641 | G8515 | G4149 | G203228 | G284992 | G1445 | G3237 | G1495 | G4135 | G1017 | G55500 | G10894 | G7015 | G212 | G10013 | G84144 | G57495 | G3620 | Phosphodiesterase IV (PDE4) (nonspecified subtype) | G6608 | G28974 | G6595 | G5321 | G10785 | G3958 | G84295 | G5914 | G1778 | G246100 | G3066 | G3238 | G2623 | G3205 | G3660 | G158931 | Inhibitor of Apoptosis Proteins (IAPs) (nonspecified subtype) | G695 | G2354 | G8883 | G6240 | G250 | G10419 | G138474 | G100526794 | Heat shock protein 90 (nonspecified subtype) | G1788 | G10481 | G57337 | G6872 | G218 | G2195 | G84033 | G94025 | G219285 | G63977 | G546 | G3326 | G6596 | G1/S-specific cyclin-E (nonspecified subtype) | G1991 | G978 | G595 | G92595 | G3239 | G5792 | G801 | G100128124 | Hedgehog Protein (nonspecified subtype) | G7040 | G4869 | G2672 | G3206 | G3559 | G51564 | G1021 | G5313 | Ephrin Receptor (nonspecified subtype) | G1432 | G4893 | G1111 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | G9212 | G2120 | G558 | Calcium channel (nonspecified subtype) | G3932 | G2938 | P6058 | G2078 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | Ribonucleoside-diphosphate reductase | G8726 | G3190 | G1263 | G164656 | G864 | G102724428 | G1050 | Lipoxygenase (nonspecified subtype) | G6046 | G6241 | Protein kinase C (nonspecified subtype) | G4595 | G7799 | G139285 | G64399 | G8243 | G598 | G25825 | G94033 | G11060 | G1436 | G415116 | G2201 | G5078 | G5885 | G79646 | G5133 | G7295 | G8743 | G1020 | P8262 | G1723 | G7161 | G9817 | G5780 | G1633 | G5152 | G83857 | G2658 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | G2139 | G3297 | G4780 | G3207 | G3417 | G3563 | G7150 | G29066 | G10320 | G3156 | G3577 | G4851 | G23451 | G1019 | G3815 | G29126 | G3106 | G9881 | G4065 | G92 | CDK9/Cyclin T1 | G1967 | G7334 | G79817 | G4277 | G4921 | G84962 | G10594 | G383 | G26338 | G168002 | G7074 | G4521 | G7852 | G93986 | G3209 | G2050 | G1813 | G7465 | G26740 | G613 | G143379 | G331 | G4968 | G23476 | G166647 | G378825 | G6016 | G4552 | G6205 | G5646 | DNA Topoisomerase II (nonspecified subtype) | G9782 | G996 | G54539 | Chaperone (nonspecified subtype) | G5211 | G55124 | G2876 | G10847 | G3400 | G673 | G5170 | G10017 | G8841 | G5595 | G1025 | G2056 | G51663 | G8444 | G3662 | G6648 | G160364 | Histone acetyltransferase (HAT) (nonspecified subtype) | G1789 | G51466 | G1043 | G952 | G140885 | G7514 | G2624 | G53347 | G3198 | G7756 | G51135 | G3312 | G151647 | G26040 | G22914 | G4778 | G6850 | G3918 | G1742 | G51428 | G5159 | G54790 | G7046 | G26277 | P16126 | G6731 | G494514 | G56894 | G55644 | G3097 | G6573 | G29128 | G3065 | G5727 | G4170 | G2894 | G2899 | G2214 | G25913 | G904 | G10326 | G5742 | G3212 | G554202 | G63036 | G23164 | G3199 | P10959 | G4609 | G25937 | G55066 | G90 | G4522 | G1452 | P16640 | G6597 | G51750 | G10236 | G30061 | G3105 | G4221 | G84985 | G9148 | G597 | G7517 | G8189 | G9429 | P16964 | G7097 | G970 | G6387 | G2475 | G10461 | G3214 | G1612 | G6795 | G2952 | G1291 | G23090 | G494551 | G54795 | G10291 | G3480 | G2538 | G9520 | G114899 | G2051 | G4622 | G5147 | G2057 | G1748 | G2324 | G867 | G945 | G9759 | G3215 | G51147 | G896 | G1400 | G3802 | G4297 | G23166 | G3418 | G3832 | G2033 | G2068 | Transforming growth factor beta (nonspecified subtype) | G3556 | G554226 | G9703 | G348807 | MLL/SET1 Complex | G23028 | G84536 | G55072 | G4352 | G2444 | G5224 | G55226 | G3216 | Mitogen-Activated Protein Kinase (nonspecified subtype) | G220359 | G54039 | G4000 | G6096 | G2321 | G8233 | G100528032 | G6263 | G54058 | G9201 | CDK2/Cyclin A | G134553 | G401137 | G6999 | G898 | G326 | G1824 | G3217 | G5894 | G386683 | G10320 | G3218 | G608 | G22894 | G8842 | G285704 | G328 | P11025 | G79661 | G23235 | G640 | G6492 | G3803 | G7010 | G8192 | G3219 | G22925 | G83549 | G84103 | G7157 | Glutaminase (nonspecified subtype) | G8575 | G3420 | G780 | G5058 | G5745 | G5925 | G5292 | G1024 | G9855 | Inosine 5'-monophosphate dehydrogenase (IMPDH) (nonspecified subtype) | G7031 | G7415 | G23199 | G6523 | G4602 | G81704 | G8019 | G10664 | G3221 | G4193 | G5422 | G3222 | G6532 | G255877 | G8835 | G3223 | G6427 | G492 | G56128 | G1485 | Hypoxia-Inducible Factor Prolyl Hydroxylase (nonspecified subtype) | G3579 | G10810 | G3224 | G4142 | G84868 | CDK2/Cyclin E | G64005 | G4067 | G23526 | Angiotensin receptor (AT) (nonspecified subtype) | G51056 | G2664 | G3804 | CDK6/Cyclin D3 | G133522 | G811 | G150094 | G4036 | G26011 | G10733 | P6884 | G1786 | G10019 | G3082 | G3225 | G4929 | G861 | G3146 | G79980 | G253959 | G5743 | G143 | G4763 | G338442 | G3226 | Cyclin A (nonspecified subtype) | G7421 | G56132 | G355 | G6091 | G29841 | G6422 | G7298 | G79982 | G23031 | G3227 | G2625 | G3654 | G1493 | G7490 | G961 | G3200 | G3228 | G11338 | G7291 | G2487 | G1234 | G18 | G22798 | G5290 | G672 | G4282 | G54587 | G55890 | G2935 | G8531 | G1728 | G31 | G2534 | G290 | G56616 | G3229 | G57520 | G580 | G10992 | G3201 | G5781 | G1387 | G4048 | G1946 | G7124 | G2944 | G332 | G124637 | P16740 | G23566 | G545 | G5788 | G341640 | G6092 | G6667 | G4645 | G5156 | G3570 | G1854 | G2322 | G100507436 | G284716 | G1814 | G4524 | G5979 | G3231 | G406883 | G4548 | P13024 | G4255 | G3635 | G7153 | G7307 | G4589 | Histone deacetylase (nonspecified subtype) | G2146 | G23077 | G3202 | G254065 | G10841 | G3481 | G5243 | G1588 | G9437 | G983 | G23097 | G25966 | G5308 | G10735 | G80206 | G1022 | G11040 | G124817 | G7292
The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Myelodysplasia, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
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