Disease

Melanoma

Review Report on Melanoma Target / Biomarker Content of Review Report on Melanoma Target / Biomarker
Melanoma


About the Disease
Melanoma, also known as malignant melanoma, is related to skin melanoma and melanoma, cutaneous malignant 1, and has symptoms including exanthema and pruritus. An important gene associated with Melanoma is BRAF (B-Raf Proto-Oncogene, Serine/Threonine Kinase), and among its related pathways/superpathways are ERK Signaling and Signal Transduction. The drugs Vindesine and Triamcinolone have been mentioned in the context of this disorder. Affiliated tissues include skin, lymph node and t cells, and related phenotypes are normal and pigmentation

Common Targets
G10381 | G2931 | G3162 | G5738 | G1630 | G1869 | G55553 | G10413 | G10859 | G22900 | G51284 | G238 | G30835 | G114548 | CDK4/Cyclin D3 | G172 | G2950 | Fibroblast Growth Factor Receptor (FGFR) (nonspecified subtype) | G6331 | G3604 | G3718 | G4325 | G8440 | G5777 | G79804 | G8795 | G9464 | G324 | G329 | G3560 | G3716 | G6847 | G102466732 | G55328 | G11200 | G6647 | Mitogen-activated protein kinase p38 (MAPK p38) (nonspecified subtype) | G4102 | G11186 | G4162 | G7078 | G5294 | G27177 | G3119 | G57381 | G596 | G7525 | G2315 | G3791 | G7014 | G4283 | G7515 | G54849 | G8912 | G1499 | G6714 | G2213 | G51185 | G83596 | G100533467 | G29851 | G4790 | G54575 | G111089941 | G154796 | G4915 | G100996941 | G2826 | G89766 | G3055 | G1142 | G116511 | Sphingosine kinase (nonspecified subtype) | G4292 | G54386 | G59 | DNA Methyltransferase (DNMT) (nonspecified subtype) | G4040 | G10039 | Na+/H+ Exchanger (NHE) (nonspecified subtype) | Vascular endothelial growth factors (VEGF) (nonspecified subtype) | G2073 | G472 | G2268 | G79991 | G253461 | G3576 | G7170 | Cyclin B (nonspecified subtype) | G85358 | G10653 | G5771 | CDK4/Cyclin D1 | G6790 | G1956 | G3949 | G25 | G93185 | P16165 | G3597 | G3845 | G1440 | P5760 | G10961 | G317754 | G6382 | G83933 | G89780 | G2936 | G4157 | G7508 | G51311 | G1012 | G647979 | G2048 | G3309 | G3553 | G3717 | G51512 | G814 | G3593 | Interleukin 17 (nonspecified subtype) | G1130 | G2150 | G2191 | G80070 | G5550 | G1048 | G4103 | G26084 | G5879 | G627 | G151393 | G7098 | G4854 | G8546 | G9595 | G406900 | G121551 | G4163 | G4241 | G9518 | P48180 | G64714 | Rho GTPase (nonspecified subtype) | G353189 | G6774 | G1846 | G7057 | G5921 | Serine/Threonine Kinase (nonspecified subtype) | G6752 | G4072 | G2335 | G55106 | G120892 | G3814 | Tyrosine-Protein Kinases Src (nonspecified subtype) | G79083 | G1017 | G3569 | G3598 | G1445 | G7015 | G4267 | G23040 | G54576 | G6722 | G1847 | G27133 | G107987026 | G1495 | G682 | G27072 | G55869 | G5590 | G105377555 | G1132 | G340273 | G84700 | G10013 | G3561 | G6608 | G5062 | G11006 | G60674 | G2263 | G4842 | G3620 | G246100 | P5755 | P5859 | G51176 | G3066 | G4109 | G52 | G3238 | G79633 | G695 | G203245 | G7376 | G701 | G4684 | G10457 | Heat shock protein 90 (nonspecified subtype) | G10419 | G10481 | G6197 | G389400 | G128861 | G58508 | G595 | G1464 | C-X-C Chemokine Receptor CXCR1/CXCR2 (IL-8 Receptor) (nonspecified subtype) | G3752 | G6778 | G3163 | G727 | G353238 | G1520 | G1991 | G89795 | G1780 | G283652 | G7040 | G8295 | G27145 | G3587 | G23022 | G5578 | G148022 | G4111 | G4489 | G4893 | G79582 | G1021 | G3371 | G3559 | P5698 | G200403 | G10280 | G3274 | G427 | G207 | G727677 | G7425 | G51564 | G1111 | Ephrin Receptor (nonspecified subtype) | G1432 | G222235 | Protein Kinase B (PKB/Akt) (nonspecified subtype) | G5137 | G9212 | G1233 | G1374 | G6352 | P6058 | G160140 | G4217 | G221718 | G5077 | G128869 | P5761 | G3932 | G4286 | G10062 | G558 | G10544 | G6272 | G7099 | G53342 | G130540 | Phosphatidylinositol 3-kinase (PI3K) (nonspecified subtype) | G153830 | G3902 | G55824 | Transforming growth factor (nonspecified subtype) | G9655 | G3479 | G4811 | G22913 | G54577 | G54901 | G102724428 | G9474 | G6046 | Protein kinase C (nonspecified subtype) | G7299 | G27436 | G1950 | G842 | G1436 | G5133 | G8784 | G105369366 | G256144 | G25790 | G8913 | G4128 | G1030 | G5728 | G64097 | P8262 | G7295 | G1020 | G1723 | G5395 | G7161 | G4990 | G80310 | G1633 | G4360 | G1019 | G4780 | G5087 | Protein Tyrosine Phosphatase (PTP) (nonspecified subtype) | G3417 | G3815 | G7150 | G2065 | G23451 | G2814 | G55054 | G3164 | G338694 | G1870 | G4254 | G2100 | G27333 | G29126 | G942 | G3106 | Glutamate Transporter (nonspecified subtype) | G634 | G6474 | G929 | G30012 | G3156 | CDK9/Cyclin T1 | G3577 | G4851 | G2776 | G55743 | G115350 | G4065 | G5291 | G5295 | G56244 | G4921 | G64127 | G2196 | G4855 | G79885 | G2618 | G8518 | G100144748 | G11113 | G383 | G675 | G462 | G55786 | G1289 | G7852 | G29952 | G3383 | G613 | P5661 | G5604 | P12578 | G6249 | P5614 | G79295 | G23411 | G2261 | G8324 | G331 | G152110 | G11197 | G1268 | Raf kinase (nonspecified subtype) | G23476 | Guanylate cyclase (nonspecified subtype) | G775 | G3123 | G4082 | G123688 | G5293 | G9214 | G6659 | G79022 | G54878 | G10630 | G3934 | G405 | G7084 | G8601 | G10154 | G3140 | G6490 | DNA Topoisomerase II (nonspecified subtype) | G80736 | G100048912 | G8894 | G6098 | G3689 | G673 | P15424 | Estrogen receptor (nonspecified subtype) | G2272 | G1025 | G7178 | G51196 | G5506 | G3600 | G1910 | G719 | G729230 | G8841 | G10507 | G5595 | G3662 | Integrin alphaIIbbeta3 (fibrinogen gpIIb/IIIa) receptor | G6566 | G7162 | G23677 | G5170 | G960 | P42808 | G92140 | G7535 | G958 | G140885 | P5756 | G1789 | G7514 | G84519 | G53347 | G2729 | G103021164 | G142 | G9448 | G6645 | G4159 | G4916 | G100499467 | G55214 | G4776 | G22914 | G2719 | G5476 | G1029 | G9420 | G3431 | G1803 | G5159 | G135 | G3702 | G6850 | G231 | G581 | G10288 | G60468 | G7757 | G84059 | G54790 | P16126 | G147700 | G54578 | G54600 | Tyrosine Kinase (nonspecified subtype) | G6794 | G26277 | G904 | G5580 | G3065 | G1725 | G4170 | G4582 | G51198 | G5727 | G4781 | G7498 | G23054 | G5742 | G1638 | G1879 | G4316 | G2185 | G2309 | G25913 | G5468 | G8924 | G1051 | G5770 | G125058 | G8398 | P40594 | G2533 | G260425 | G2071 | G4507 | G101929467 | G2903 | G3601 | G151278 | G168537 | G406992 | G4609 | G51280 | G857 | G43 | G208 | G5054 | G841 | G2833 | G706 | G330 | G1649 | G920 | G4914 | G346007 | G85415 | G2932 | G116173 | Heme Oxygenase (HO) (nonspecified subtype) | G369 | G256957 | Interferon (nonspecified subtype) | G11284 | G1284 | G83706 | G3090 | G3105 | G53 | G4221 | G4691 | G8859 | G94 | G6404 | G64218 | G3990 | G9429 | G597 | P16964 | G3921 | G285626 | G57537 | G6387 | G7097 | G2475 | G104355138 | G931 | G970 | G1238 | P18298 | CDK1/Cyclin B | G497258 | G5140 | G85416 | G1009 | G1147 | G1612 | G6910 | G84062 | G10461 | G9378 | G22918 | G105369749 | G10683 | G57510 | P15736 | G255426 | G257 | G3480 | G3630 | G2051 | G2324 | G5507 | Elastase (nonspecified subtype) | G4600 | G9971 | G81552 | G5289 | G100188947 | G896 | G107984647 | G867 | G5584 | P5753 | Vascular endothelial growth factor receptor (VEGFR) (nonspecified subtype) | G1136 | G146853 | G64806 | G2798 | G3832 | G6775 | G1906 | G2068 | G23166 | G1795 | G2099 | Actin (nonspecified subtype) | G79037 | G56172 | G1437 | Sodium channel (nonspecified subtype) | G23028 | Caspase (nonspecified subtype) | Mitogen-Activated Protein Kinase (nonspecified subtype) | G2444 | G6662 | G80243 | G2523 | Platelet-Derived Growth Factor Receptor (nonspecified subtype) | G3953 | G7979 | G51438 | Sterol O-acyltransferase (ACAT) (nonspecified subtype) | G7130 | G2321 | G836 | G2260 | G5888 | G5915 | G1917 | G54796 | G1116 | G3568 | G7042 | G4318 | G100528032 | CDK2/Cyclin A | G6323 | G284217 | G916 | G5894 | G64135 | Heat shock protein 70 (nonspecified subtype) | G90417 | G6999 | P23236 | G151888 | G8842 | G3217 | G3778 | G2188 | G81037 | G84444 | G2911 | G10725 | G640 | G3664 | G7010 | G7157 | G219931 | G2264 | G23235 | G27346 | G8927 | G1969 | G27036 | G8754 | G10188 | P5757 | Poly [ADP-ribose] polymerase (nonspecified subtype) | G6392 | Adenosine receptor (nonspecified subtype) | G780 | G4948 | G51151 | G4155 | G9508 | G3099 | Protein Tyrosine Phosphatase Type IVA (nonspecified subtype) | G4862 | G335 | G3603 | G3627 | G51206 | G8756 | G1513 | G760 | G1027 | G9123 | G3394 | G4193 | G7415 | G65057 | G7093 | G11126 | G8019 | G2638 | G5618 | G57016 | G22807 | G8558 | G123041 | G22861 | G953 | G967 | G9706 | G356 | G1485 | G107985067 | G4317 | G7293 | G56128 | G9125 | G59067 | G6185 | G3579 | G2072 | G1108 | Aurora Kinase (nonspecified subtype) | G6663 | G3224 | G4067 | G2548 | G84868 | G8654 | G55768 | G201633 | G7273 | G1642 | G50604 | G5537 | CDK6/Cyclin D3 | P6348 | G79728 | G55532 | G133522 | G150094 | P6884 | G1786 | G4313 | G1508 | G4036 | G2175 | G2615 | G100529262 | G5605 | G3082 | G5743 | G29924 | G4763 | G4929 | G54106 | Cyclin A (nonspecified subtype) | G177 | G7421 | G4907 | G23705 | G83734 | G262 | G8764 | G100529264 | G10135 | G4843 | G10038 | Nitric oxide synthase (NOS) (nonspecified subtype) | G6556 | G4233 | G53353 | G5603 | G355 | G55770 | G943 | G338 | G1493 | G4644 | G23007 | G5027 | G5190 | G3458 | G124045 | G367 | G7490 | G7507 | G2625 | G55884 | G3806 | G5290 | G100996521 | G961 | G5871 | G64840 | G101927549 | G940 | G11103 | G7003 | G4920 | G27232 | G925 | G1234 | G1280 | P29419 | G672 | G10298 | G6478 | G7306 | G761 | G4323 | G4613 | G79858 | G2064 | G213 | G79068 | G10000 | G2935 | G4363 | G102723526 | G7124 | G5010 | G2534 | G2778 | G1293 | G2267 | G4978 | G5407 | G57591 | G340061 | G57644 | G5781 | G64115 | Dual Specificity Mitogen-Activated Protein Kinase Kinase (MEK) (nonspecified subtype) | Potassium Channels (nonspecified subtype) | G8314 | G55340 | G1387 | G8737 | G91039 | G332 | G7373 | G6373 | G7004 | G5156 | G83999 | G2767 | G10319 | P16740 | G81168 | Melanocortin receptor (nonspecified subtype) | G79444 | G2322 | G868 | G5788 | P42105 | G254879 | G545 | G8714 | G341640 | G3570 | G3586 | G7980 | G5979 | G100507436 | Voltage-Gated Calcium Channel alpha-2/delta (nonspecified subtype) | G4100 | G4255 | G2247 | G240 | G10495 | G3175 | G4607 | G3565 | G401237 | G4161 | G7428 | G3455 | G384 | G7153 | G80381 | G8408 | G921 | G677775 | alpha-Mannosidase (nonspecified subtype) | Histone deacetylase (nonspecified subtype) | G5266 | G2146 | G5139 | G5243 | G574501 | G1843 | G983 | G4057 | G1770 | G1138 | G1588 | G26018 | G9229 | P5682 | G7013 | G7096 | G4953 | G2735 | G3596 | G441108 | G23586 | Monoamine oxidase (MAO) (nonspecified subtype) | G84634 | G10666 | G149233 | G7422 | G23532 | G930 | G7292 | G3107 | G7048 | G7184 | G79679

The "Target / Biomarker Review Report" is a comprehensive and customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about the Target(s) / Biomarker(s) of your choice related to Melanoma, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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