DSG3: A Drug Target / Disease Biomarker (G1830)

Target Name: DSG3

NCBI ID: G1830

DSG3

DSG3: A Drug Target / Disease Biomarker

DSG3 (double stranded GTPase-activating protein 3) is a protein that is expressed in various tissues throughout the body, including the brain, heart, and kidneys. It is a key regulator of gene expression and has been implicated in a number of cellular processes, including cell signaling, DNA replication, and stress response. As a result, DSG3 has been identified as a potential drug target and biomarker for a variety of diseases.

DSG3 is a protein that is composed of two identical subunits that are held together by a disulfide bond. The subunits contain a catalytic domain and a transmembrane region. The catalytic domain is responsible for the protein's catalytic activity and is the region that interacts with other molecules to perform its functions. The transmembrane region is responsible for the protein's ability to interact with the cell's cytoskeleton and for its localization to specific cellular structures.

DSG3 is involved in a number of cellular processes that are important for maintaining cellular homeostasis. For example, it is involved in the regulation of cell signaling pathways, including the TGF-β pathway. This pathway is involved in the regulation of cell growth, differentiation, and survival, and is a key factor in the development and progression of many diseases, including cancer.

DSG3 is also involved in the regulation of DNA replication. DNA replication is a critical process that is essential for the maintenance of genetic diversity and for the development and repair of new DNA in the cell. DSG3 is involved in the regulation of DNA replication by activating the DNA replication machinery and by preventing the degradation of damaged DNA.

In addition to its role in cell signaling and DNA replication, DSG3 is also involved in the regulation of stress response. Stress is a critical factor that can disrupt cellular homeostasis and cause a variety of cellular processes to go awry. DSG3 is involved in the regulation of stress response by activating the stress response pathway and by preventing the accumulation of stress-induced damage in the cell.

DSG3 has also been implicated in a variety of diseases, including cancer. For example, studies have suggested that high levels of DSG3 expression are associated with poor prognosis in many types of cancer. Additionally, DSG3 has been shown to promote the growth and survival of cancer cells, which suggests that it may be a useful biomarker for cancer.

In conclusion, DSG3 is a protein that is involved in a number of important cellular processes that are essential for maintaining cellular homeostasis. Its role in cell signaling, DNA replication, and stress response makes it a potential drug target and biomarker for a variety of diseases. Further research is needed to fully understand the functions of DSG3 and to develop effective treatments for the prevention and treatment of these diseases.

Protein Name: Desmoglein 3

Functions: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion

The "DSG3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about DSG3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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