FABP5: A Potential Target Or Biomarker for Cancer, Neurodegenerative Diseases and Autoimmune Disorders

Target Name: FABP5

NCBI ID: G2171

FABP5

FABP5: A Potential Target Or Biomarker for Cancer, Neurodegenerative Diseases and Autoimmune Disorders

FABP5, short for Fas-associated protein 5, is a protein that is expressed in various tissues throughout the body, including the brain, heart, lungs, and gastrointestinal tract. It is a member of the Fas protein family, which is known for their role in cell signaling and memory.

FABP5 has been identified as a potential drug target or biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and expression pattern in different tissues make it an attractive target for researchers to study.

One of the key reasons why FABP5 has gained so much attention is its role in cancer. Cancer is a leading cause of death worldwide, and there is a need for new treatments to address the increasing number of cases. FABP5 has been shown to be involved in various cellular processes that are critical for cancer development, including cell signaling, angiogenesis, and immune evasion.

FABP5 has been shown to promote the growth and survival of cancer cells. In one study, researchers found that FABP5 was highly expressed in human cancer tissues and that it was associated with cancer progression. They also found that inhibiting FABP5 reduced the growth and survival of cancer cells.

Another potential drug target for FABP5 is its role in neurodegenerative diseases. Neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, are progressive conditions that affect the brain and cause progressive symptoms. FABP5 has been shown to be involved in the development and progression of these diseases, and it has been shown to be a potential therapeutic target.

FABP5 has been shown to contribute to the development of neurodegenerative diseases by promoting the formation of axonal sprouts, which are thought to play a key role in the progression of neurodegenerative diseases. In one study, researchers found that mice that were genetically modified to lack FABP5 had reduced axonal sprouts and were less likely to develop neurodegenerative diseases.

FABP5 has also been shown to be involved in autoimmune disorders. Autoimmune disorders, such as rheumatoid arthritis and multiple sclerosis, are conditions in which the immune system attacks the body's own tissues. FABP5 has been shown to be involved in the development and progression of these disorders, and it has been shown to be a potential therapeutic target.

In one study, researchers found that FABP5 was highly expressed in rheumatoid arthritis tissues and that it was associated with the development of the disease. They also found that inhibiting FABP5 reduced the production of antibodies, which are a hallmark of rheumatoid arthritis.

FABP5 is also a potential biomarker for cancer, as it has been shown to be expressed in various types of cancer. This makes it an attractive target for researchers to study and to develop new diagnostic tests or biomarkers for cancer.

In conclusion, FABP5 is a protein that has gained significant attention due to its role in various cellular processes that are critical for cancer, neurodegenerative diseases, and autoimmune disorders. Its unique structure and expression pattern in different tissues make it an attractive target for researchers to study and to develop new treatments or biomarkers for these diseases. Further research is needed to fully understand the role of FABP5 in these diseases and to develop new treatments or biomarkers for them.

Protein Name: Fatty Acid Binding Protein 5

Functions: Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors (PubMed:22170058, PubMed:21395585). Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta; which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation (By similarity). May be involved in keratinocyte differentiation (PubMed:8092987)

The "FABP5 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FABP5 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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