Target Name: PATL1
NCBI ID: G219988
Review Report on PATL1 Target / Biomarker Content of Review Report on PATL1 Target / Biomarker
PATL1
Other Name(s): hPat1b | Protein PAT1 homolog b | PAT1-like protein 1 | FLJ36874 | Protein PAT1 homolog 1 | PAT1 homolog 1, processing body mRNA decay factor | MGC125672 | MGC125671 | PATL1_HUMAN | protein associated with topoisomerase II homolog 1 | OTTHUMP00000235907 | protein PAT1 homolog b | Pat1b

PATL1: A Protein with Potential Therapeutic Applications

PATL1 (hPat1b) is a protein that is expressed in various tissues of the body, including the brain, heart, and kidneys. It is a member of the Patl family of proteins, which are known to play a role in cell signaling and signaling pathways. While the exact function of PATL1 is not yet fully understood, it is possible that it may be a drug target or biomarker.

Drug Target Potential

PATL1 has been identified as a potential drug target due to its involvement in several cellular processes that are important for human health. One of the key functions of PATL1 is its role in the regulation of cell signaling pathways, including the regulation of cell proliferation and apoptosis.

PATL1 has been shown to play a role in the regulation of cell proliferation by controlling the activity of the transcription factor, p53. This is important because p53 is a well-known protein that is involved in the regulation of cell growth and division, and is often targeted by drugs that are designed to inhibit its activity.

In addition to its role in cell proliferation, PATL1 has also been shown to play a role in the regulation of cell apoptosis, which is the process by which cells die naturally. PATL1 has been shown to regulate the activity of the executor of cell apoptosis, which is the protein called Bax.

Biomarker Potential

PATL1 may also be a useful biomarker for certain diseases. For example, PATL1 has been shown to be expressed in the brains of individuals with Alzheimer's disease, which is a degenerative brain disorder that is characterized by the progressive loss of brain cells.

In addition, PATL1 has also been shown to be expressed in the hearts of individuals with heart failure, which is a condition in which the heart is not able to pump enough blood to meet the body's needs.

Potential Therapeutic Strategies

Given the potential role of PATL1 in cell signaling pathways and its involvement in the regulation of cell proliferation and apoptosis, there is ongoing research into the potential therapeutic applications of PATL1.

One approach that is being explored is the use of small molecules to inhibit the activity of PATL1. This approach is based on the idea that by reducing the activity of PATL1, it will be possible to reduce the regulation of cell signaling pathways and potentially improve the health of a variety of conditions.

Another approach that is being explored is the use of antibodies to target PATL1 directly. This approach is based on the idea that by binding to PATL1, antibodies will be able to prevent it from interacting with other proteins and will potentially reduce the regulation of cell signaling pathways.

Conclusion

PATL1 is a protein that has been identified as having potential therapeutic applications due to its involvement in the regulation of cell signaling pathways and its involvement in the regulation of cell proliferation and apoptosis. While further research is needed to fully understand the function of PATL1 and its potential therapeutic applications, it is clear that PATL1 is an important protein that will continue to be an focus of research in the years to come.

Protein Name: PAT1 Homolog 1, Processing Body MRNA Decay Factor

Functions: RNA-binding protein involved in deadenylation-dependent decapping of mRNAs, leading to the degradation of mRNAs (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261). Acts as a scaffold protein that connects deadenylation and decapping machinery (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261). Required for cytoplasmic mRNA processing body (P-body) assembly (PubMed:17936923, PubMed:20543818, PubMed:20584987, PubMed:20852261)

The "PATL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PATL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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