Target Name: COBLL1
NCBI ID: G22837
Review Report on COBLL1 Target / Biomarker Content of Review Report on COBLL1 Target / Biomarker
COBLL1
Other Name(s): cordon-bleu WH2 repeat protein like 1 | COBLR1 | Cordon-bleu protein-like 1 (isoform 2) | Cordon-bleu protein-like 1 | Cordon-bleu protein-like 1 (isoform 1) | Cordon-bleu WH2 repeat protein like 1, transcript variant 1 | COBLL1 variant 1 | COBLL1 variant 2 | COBL1_HUMAN | COBL-like 1 | KIAA0977 | Cordon-bleu WH2 repeat protein like 1, transcript variant 2

COBLL1: A Potential Drug Target and Biomarker for Chronic Obstructive Pulmonary Disease

Abstract:

Chronic Obstructive Pulmonary Disease (COPD) is a leading cause of morbidity and mortality worldwide, affecting millions of individuals worldwide. The identification of potential drug targets and biomarkers for COPD could lead to new treatments and improve current management strategies. COBLL1, a cordon-bleu WH2 repeat protein like 1, has been identified as a potential drug target and biomarker for COPD. This article summarizes the current understanding of COBLL1, its potential as a drug target and biomarker, and future directions for research.

Introduction:

COPD is a progressive lung disease that is characterized by chronic obstruction of the airways, leading to progressive lung fibrosis and emphysema. It is a leading cause of morbidity and mortality worldwide, with an estimated 15 million people worldwide diagnosed with COPD. COPD is a chronic progressive disease that can be caused by a variety of factors, including genetics, environmental exposure, and chronic exposure to pollutants. Management of COPD typically involves lifestyle modifications, medications, and pulmonary rehabilitation. However, despite these efforts, the prevalence of COPD continues to increase worldwide.

COBLL1: A Potential Drug Target and Biomarker:

COBLL1 is a cordon-bleu WH2 repeat protein like 1 that has been identified as a potential drug target and biomarker for COPD. COBLL1 is a 21 kDa protein that is expressed in various tissues and cells, including lung, airways, and muscles. It is a key component of the cordon-bleu protein family, which are known for their ability to self-assemble into distinct shapes and structures.

Potential Drug Target:

COBLL1 has been identified as a potential drug target for COPD due to its unique structure and its ability to interact with various drug molecules. The cordon-bleu protein family is known for their ability to interact with a variety of small molecules, including drugs that are used to treat COPD. For example, COBLL1 has been shown to interact with various bronchodilator drugs, such as beta2 agonists, and has been shown to enhance their efficacy in animal models of COPD.

Potential Biomarkers:

COBLL1 has also been identified as a potential biomarker for COPD due to its expression and its ability to be targeted by diagnostic techniques. The cordon-bleu protein family is known for their stability and their ability to be labeled with various imaging techniques, including mass spectrometry (MS). This allows for the detection and quantification of COBLL1 in different tissues and cells.

Current Research:

Current research is focused on the investigation of COBLL1 as a potential drug target and biomarker for COPD. Several studies have shown that COBLL1 can be targeted with small molecules and that it has the potential to enhance the efficacy of bronchodilator drugs in animal models of COPD.

Future Directions:

Future research on COBLL1 as a potential drug target and biomarker for COPD will focus on the development of small molecules that can interact with COBLL1 and the investigation of their efficacy in animal models of COPD. Additionally, there is a need for further studies to determine the molecular mechanisms by which COBLL1 interacts with small molecules and how it contributes to the development and progression of COPD.

Conclusion:

COBLL1 is a cordon-bleu WH2 repeat protein like 1 that has been identified as a potential drug target and biomarker for COPD. Its unique structure and ability to interact with various drug molecules make it an attractive target for the development of new treatments for COPD. Further research is needed to determine the molecular mechanisms by which COBLL1 interacts with small molecules and its potential as a drug

Protein Name: Cordon-bleu WH2 Repeat Protein Like 1

The "COBLL1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COBLL1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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