Target Name: COMMD6
NCBI ID: G170622
Review Report on COMMD6 Target / Biomarker Content of Review Report on COMMD6 Target / Biomarker
COMMD6
Other Name(s): COMD6_HUMAN | COMM domain containing 6 | COMM domain containing 6, transcript variant 1 | COMM domain containing 6, transcript variant 2 | COMM domain-containing protein 6 | COMMD6 variant 2 | COMMD6 variant 1 | Acrg embryonic lethality minimal region ortholog | COMM domain-containing protein 6 (isoform b) | Acrg | COMM domain-containing protein 6 (isoform a)

COMMD6: A Potential Drug Target and Biomarker for Multiple Chronic Diseases

COMMD6 is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell division and has been implicated in the development and progression of multiple chronic diseases. While the exact function of COMMD6 is not yet fully understood, research has identified several potential drug targets and biomarkers that may interact with this protein. In this article, we will explore the potential implications of COMMD6 as a drug target and biomarker for multiple chronic diseases.

Potential Drug Targets

COMMD6 has been shown to play a role in the regulation of cell division and has been implicated in the development of various chronic diseases. One of the most well-known functions of COMMD6 is its role in the regulation of cancer cell growth. studies have shown that COMMD6 plays a negative role in the growth and survival of cancer cells, by inhibiting the activity of the oncogene p53. This means that COMMD6 may be an attractive target for cancer therapeutic strategies.

Another potential drug target for COMMD6 is its role in the regulation of neurodegenerative diseases. studies have shown that COMMD6 is involved in the regulation of neurotransmitter synthesis and release, which is important for the function of the nervous system. Therefore, COMMD6 may be a potential target for neurodegenerative diseases such as Alzheimer's and Parkinson's disease.

Potential Biomarkers

COMMD6 has also been shown to be involved in the regulation of cell death, which is an important aspect of many chronic diseases. The regulation of cell death is critical for maintaining tissue homeostasis and is often disrupted in chronic diseases. Therefore, COMMD6 may be a potential biomarker for multiple chronic diseases.

One of the key features of COMMD6 is its ability to induce cell death in a controlled manner. Studies have shown that COMMD6 can induce cell death through several different mechanisms, including the production of reactive oxygen species (ROS) and the inhibition of cell survival signals. This means that COMMD6 may be an attractive target for drugs that are designed to induce cell death in chronic diseases.

Another potential biomarker for COMMD6 is its ability to regulate inflammation. Studies have shown that COMMD6 is involved in the regulation of inflammation, which is a key aspect of many chronic diseases. Therefore, COMMD6 may be a potential target for drugs that are designed to treat chronic inflammatory diseases.

Conclusion

In conclusion, COMMD6 is a protein that has been shown to play a role in the regulation of cell division and has been implicated in the development and progression of multiple chronic diseases. As a result, COMMD6 may be an attractive target for drug development for a variety of chronic diseases. The regulation of cell death, the regulation of neurotransmitter synthesis and release, and the regulation of inflammation are all potential targets for COMMD6. Further research is needed to fully understand the function of COMMD6 and its potential as a drug target and biomarker for multiple chronic diseases.

Protein Name: COMM Domain Containing 6

Functions: May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B. Inhibits TNF-induced NFKB1 activation

The "COMMD6 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COMMD6 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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