Target Name: COMP
NCBI ID: G1311
Review Report on COMP Target / Biomarker Content of Review Report on COMP Target / Biomarker
COMP
Other Name(s): COMP_HUMAN | cartilage oligomeric matrix protein | pseudoachondroplasia (epiphyseal dysplasia 1, multiple) | THBS5 | PSACH | Cartilage oligomeric matrix protein | EDM1 | Epiphyseal dysplasia, multiple 1 | Thrombospondin-5 | thrombospondin-5 | CTS2 | TSP5 | cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple) | EPD1 | MED

COMP: A Potential Drug Target for Many Biological Processes

COMP (COMP_HUMAN), a protein that is expressed in the human body, has been identified as a potential drug target or biomarker. The protein is involved in the regulation of cellular processes that are important for many different biological processes, including cell growth, differentiation, and survival.

COMP is a transmembrane protein that is expressed in a variety of tissues and cells in the human body. It is involved in the regulation of cellular processes that are important for many different biological processes, including cell growth, differentiation, and survival. The protein is expressed in the brain, heart, and kidneys, among other tissues, and is also found in the bloodstream.

One of the key functions of COMP is its role in the regulation of cell growth. Comp is involved in the inhibition of cell proliferation, which is the process by which cells divide and grow. This is important for the development and maintenance of tissues and organs, as well as for the growth and development of the fetus.

Another function of COMP is its role in the regulation of cell differentiation. Comp is involved in the regulation of the differentiation of cells into different types of tissues and organs. This is important for the development and maintenance of tissues and organs, as well as for repair and regeneration.

Comp is also involved in the regulation of cell survival. The protein is involved in the inhibition of cell death, which is the process by which cells are destroyed or damaged and are no longer able to function. This is important for the development and maintenance of tissues and organs, as well as for the regulation of the immune system.

In addition to its role in cell growth, COMP is also involved in the regulation of many other cellular processes that are important for the health and function of the body. The protein is involved in the regulation of cell signaling, which is the process by which cells communicate with each other and coordinate their activities. It is also involved in the regulation of cell migration, which is the movement of cells to different locations in the body.

COMP is also a potential biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. The protein is often expressed in high levels in tissues and cells that are affected by these types of diseases, and may be a useful target for diagnostic tests and therapies.

In conclusion, COMP is a protein that is expressed in the human body that is involved in the regulation of cellular processes that are important for many different biological processes. The protein is expressed in a variety of tissues and cells in the body, including the brain, heart, and kidneys, and is also found in the bloodstream. COMP is a potential drug target or biomarker for a variety of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. Further research is needed to fully understand the role of COMP in the regulation of cellular processes and its potential as a therapeutic target.

Protein Name: Cartilage Oligomeric Matrix Protein

Functions: Plays a role in the structural integrity of cartilage via its interaction with other extracellular matrix proteins such as the collagens and fibronectin. Can mediate the interaction of chondrocytes with the cartilage extracellular matrix through interaction with cell surface integrin receptors (PubMed:16542502, PubMed:16051604). Could play a role in the pathogenesis of osteoarthritis (PubMed:16542502). Potent suppressor of apoptosis in both primary chondrocytes and transformed cells. Suppresses apoptosis by blocking the activation of caspase-3 and by inducing the IAP family of survival proteins (BIRC3, BIRC2, BIRC5 and XIAP) (PubMed:17993464). Essential for maintaining a vascular smooth muscle cells (VSMCs) contractile/differentiated phenotype under physiological and pathological stimuli. Maintains this phenotype of VSMCs by interacting with ITGA7 (By similarity)

The "COMP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COMP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

Complement Complex | Complement component 1q | Complement component C1 | Complement component C8 | COMT | COMTD1 | Condensin complex | Condensin-2 complex | Conserved oligomeric Golgi complex | COP1 | COP9 signalosome complex | COPA | COPB1 | COPB2 | COPB2-DT | COPE | COPG1 | COPG2 | COPG2IT1 | COPRS | COPS2 | COPS3 | COPS4 | COPS5 | COPS6 | COPS7A | COPS7B | COPS8 | COPS8P3 | COPS9 | COPZ1 | COPZ2 | COQ10A | COQ10B | COQ2 | COQ3 | COQ4 | COQ5 | COQ6 | COQ7 | COQ8A | COQ8B | COQ9 | CORIN | CORO1A | CORO1B | CORO1C | CORO2A | CORO2B | CORO6 | CORO7 | CORT | Corticotropin-Releasing Factor (CRF) Receptor | COTL1 | COTL1P1 | COX1 | COX10 | COX10-DT | COX11 | COX14 | COX15 | COX16 | COX17 | COX18 | COX19 | COX2 | COX20 | COX3 | COX4I1 | COX4I1P1 | COX4I2 | COX5A | COX5B | COX6A1 | COX6A2 | COX6B1 | COX6B1P2 | COX6B1P3 | COX6B1P5 | COX6B1P7 | COX6B2 | COX6C | COX6CP1 | COX6CP17 | COX7A1 | COX7A2 | COX7A2L | COX7A2P2 | COX7B | COX7B2 | COX7C | COX7CP1 | COX8A | COX8BP | COX8C | CP | CPA1 | CPA2 | CPA3 | CPA4