Target Name: COL15A1
NCBI ID: G1306
Review Report on COL15A1 Target / Biomarker Content of Review Report on COL15A1 Target / Biomarker
COL15A1
Other Name(s): Restin-2 | Restin-I | Related to endostatin | Collagen alpha 1(XV) chain | collagen type XV proteoglycan | endostatin-XV | Collagen XV, alpha-1 polypeptide | collagen type XV alpha 1 chain | Restin-3 | Endostatin-XV | Restin | Collagen alpha-1(XV) chain | Restin-4 | Restin-II | Restin-III | collagen, type XV, alpha 1 | restin | Collagen type XV alpha 1 chain | Restin-IV | collagen XV, alpha-1 polypeptide | COFA1_HUMAN

A Promising Drug Target: COL15A1 (Restin-2)

Abstract:

COL15A1 (Restin-2) is a highly expressed gene in various tissues, including the liver, lung, and heart. It has been identified as a potential drug target and biomarker for various diseases, including cancer. This article will discuss the biology of COL15A1 , its potential as a drug target, and its potential as a biomarker for disease.

Introduction:

The gene COL15A1 (Restin-2) has been identified as a potential drug target and biomarker for various diseases. It is highly expressed in various tissues, including the liver, lung, and heart, and has been associated with various diseases, including cancer. This article will discuss the biology of COL15A1, its potential as a drug target, and its potential as a biomarker for disease.

Biology of COL15A1:

COL15A1 is a 19 kDa transmembrane protein that is expressed in various tissues, including the liver, lung, and heart. It is a member of the K-type channel subfamily and is involved in the regulation of ion and water transport. COL15A1 has been shown to play a role in various physiological processes, including cell signaling, inflammation, and fibrosis.

Potential as a Drug Target:

COL15A1 has been identified as a potential drug target due to its unique biological properties and its involvement in various diseases. Several studies have shown that inhibition of COL15A1 can lead to the inhibition of various cellular processes, including cell signaling, angiogenesis, and fibrosis. Additionally, several compounds have been shown to be effective in inhibiting the activity of COL15A1, including small molecules, peptides, and antibodies.

Potential as a Biomarker:

COL15A1 has also been identified as a potential biomarker for various diseases, including cancer. Its expression has been shown to be elevated in various types of cancer, including breast, lung, and ovarian cancer. Additionally, studies have shown that the expression of COL15A1 is associated with poor prognosis in patients with cancer.

Conclusion:

In conclusion, COL15A1 (Restin-2) is a promising drug target and biomarker for various diseases. Its unique biology and its involvement in various physiological processes make it an attractive target for drug development. Additionally, its potential as a biomarker for cancer makes it an important compound to study in the context of disease diagnosis and prognosis. Further research is needed to fully understand the biology of COL15A1 and its potential as a drug and biomarker.

Protein Name: Collagen Type XV Alpha 1 Chain

Functions: Structural protein that stabilizes microvessels and muscle cells, both in heart and in skeletal muscle

The "COL15A1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about COL15A1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

COL16A1 | COL17A1 | COL18A1 | COL18A1-AS1 | COL19A1 | COL1A1 | COL1A2 | COL1A2-AS1 | COL20A1 | COL21A1 | COL22A1 | COL23A1 | COL24A1 | COL25A1 | COL26A1 | COL27A1 | COL28A1 | COL2A1 | COL3A1 | COL4A1 | COL4A2 | COL4A2-AS1 | COL4A3 | COL4A4 | COL4A5 | COL4A6 | COL5A1 | COL5A2 | COL5A3 | COL6A1 | COL6A2 | COL6A3 | COL6A4P1 | COL6A4P2 | COL6A5 | COL6A6 | COL7A1 | COL8A1 | COL8A2 | COL9A1 | COL9A2 | COL9A3 | COLCA1 | COLEC10 | COLEC11 | COLEC12 | COLGALT1 | COLGALT2 | Colipase-Lipase complex | Collagen | Collagen alpha-1(I) chain | Collagen I | Collagen IV | Collagen IX | Collagen V | Collagen VI | Collagen VIII | Collagen XI | Collagenase | Colony-stimulating factor | COLQ | COMETT | COMMD1 | COMMD10 | COMMD2 | COMMD3 | COMMD3-BMI1 | COMMD4 | COMMD5 | COMMD6 | COMMD7 | COMMD8 | COMMD9 | COMP | Complement Complex | Complement component 1q | Complement component C1 | Complement component C8 | COMT | COMTD1 | Condensin complex | Condensin-2 complex | Conserved oligomeric Golgi complex | COP1 | COP9 signalosome complex | COPA | COPB1 | COPB2 | COPB2-DT | COPE | COPG1 | COPG2 | COPG2IT1 | COPRS | COPS2 | COPS3 | COPS4 | COPS5 | COPS6 | COPS7A