Target Name: PPP6R1
NCBI ID: G22870
Review Report on PPP6R1 Target / Biomarker Content of Review Report on PPP6R1 Target / Biomarker
PPP6R1
Other Name(s): PP6R1_HUMAN | PP6R1 | Serine/threonine-protein phosphatase 6 regulatory subunit 1 | protein phosphatase 6 regulatory subunit 1 | SAPS1 | KIAA1115 | SAPS domain family member 1 | SAPS domain family, member 1 | SAP190 | Protein phosphatase 6 regulatory subunit 1

PP6R1: A Potential Drug Target and Biomarker

PP6R1 (PP6R1_HUMAN) is a protein that is expressed in various tissues of the human body. It is a member of the protein family known as PPI (phospholipid-protein) and is involved in the intracellular signaling pathway known as the PI3K/Akt signaling pathway . This pathway is involved in various cellular processes, including cell signaling, cell adhesion, and inflammation.

The PPI signaling pathway is a critical pathway that regulates various cellular processes in the body. It is involved in the regulation of ion channels, protein kinase, and other signaling pathways that are involved in the regulation of cellular processes. in the regulation of various cellular signaling pathways, including the regulation of cell growth, cell differentiation, and cell survival.

PP6R1 is a protein that is involved in the regulation of the PPI signaling pathway. It is a 21-kDa protein that is expressed in various tissues of the human body, including brain, heart, liver, and kidney. of cellular processes, including the regulation of ion channels, protein kinases, and other signaling pathways that are involved in the regulation of cellular processes.

Drug Targeting

PP6R1 is a drug target that is involved in various cellular processes. As a drug target, PPP6R1 can be targeted with various drugs, including small molecules, antibodies, and other therapeutic agents.

Small molecules are a common drug delivery system that are used to target proteins involved in various cellular processes. Small molecules can interact with PPP6R1 and alter its stability, function, or activity. For example, small molecules such as inhibitors of the PPI signaling pathway can be used to reduce the activity of PPP6R1 and inhibit its function in the regulation of cellular processes.

Antibodies are another drug delivery system that can be used to target proteins involved in various cellular processes. Antibodies can interact with PPP6R1 and alter its stability, function, or activity. For example, antibodies such as monoclonal antibodies (MCOs) or polyclonal antibodies (PCAs ) can be used to bind to PPP6R1 and inhibit its function in the regulation of cellular processes.

In addition to small molecules and antibodies, other therapeutic agents can also be used to target PPP6R1. For example, genetic modifiers can be used to alter the expression level of PPP6R1. By modifying the expression level of PPP6R1, researchers can reduce or increase its function in the regulation of cellular processes.

Biomarker

PP6R1 is also a potential biomarker for various diseases. The PPI signaling pathway is involved in the regulation of various cellular processes, including cell signaling, cell adhesion, and inflammation. Therefore, changes in the expression level of PPP6R1 can be an indication of certain diseases.

For example, PPP6R1 levels have been reported to be reduced in various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. These changes in PPP6R1 levels can be used as a biomarker to diagnose or monitor these diseases.

Conclusion

PP6R1 (PP6R1_HUMAN) is a protein that is involved in the regulation of the PPI signaling pathway. It is a potential drug target and can be targeted with small molecules, antibodies, and other therapeutic agents. PPP6R1 is also a potential biomarker for various diseases. Further research is needed to fully understand the role of PPP6R1 in cellular processes and its potential as a drug target and biomarker.

Protein Name: Protein Phosphatase 6 Regulatory Subunit 1

Functions: Regulatory subunit of protein phosphatase 6 (PP6). May function as a scaffolding PP6 subunit. Involved in the PP6-mediated dephosphorylation of NFKBIE opposing its degradation in response to TNF-alpha

The "PPP6R1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about PPP6R1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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