Target Name: MPRIP
NCBI ID: G23164
Review Report on MPRIP Target / Biomarker Content of Review Report on MPRIP Target / Biomarker
MPRIP
Other Name(s): Myosin phosphatase-Rho interacting protein | M-RIP | MPRIP variant 1 | MPRIP_HUMAN | myosin phosphatase Rho interacting protein | Myosin phosphatase Rho-interacting protein | Myosin phosphatase Rho-interacting protein (isoform 1) | Rho interacting protein 3 | Rho-interacting protein 3 | RHOIP3 | OTTHUMP00000065509 | p116Rip | MRIP | Myosin phosphatase Rho interacting protein, transcript variant 1 | OTTHUMP00000065508 | RIP3 | KIAA0864

MPRIP: A Potential Drug Target Or Biomarker

MPRIP (Myosin Phosphatase-Rho Interacting Protein) is a protein that is expressed in various tissues and cells throughout the body. It is a key regulator of muscle contractions and has been implicated in a number of diseases, including muscular dystrophy, cancer, and neurodegenerative diseases. In this article, we will discuss the research on MPRIP and its potential as a drug target or biomarker.

MPRIP is a protein that is composed of 129 amino acid residues and has a calculated molecular mass of 19.1 kDa. It is a member of the Myosin Phosphatase family and is expressed in a variety of tissues, including muscle, heart, brain, and plasma. MPRIP is primarily localized to the cytoplasm of muscle cells and is thought to play a role in regulating muscle contractions.

One of the most significant functions of MPRIP is its role in regulating the activity of myosin, a protein that is involved in muscle contraction. Myosin is composed of a protein subunit and a nucleotide subunit, and it is regulated by a variety of factors, including MPRIP. MPRIP has been shown to interact with myosin and to regulate its activity in a variety of ways.

One of the key functions of MPRIP is its role in the regulation of muscle strength and endurance. MPRIP has been shown to play a role in the regulation of muscle protein synthesis and in the maintenance of muscle mass. It has also been shown to play a role in the regulation of muscle fiber type and in the development of muscle diseases, including muscular dystrophy.

In addition to its role in regulating muscle contractions, MPRIP is also thought to have a variety of other functions. For example, it has been shown to play a role in the regulation of cell survival and in the regulation of inflammation. It is also thought to play a role in the regulation of cell signaling pathways, including the PI3K/Akt signaling pathway.

MPRIP is also of interest as a potential drug target or biomarker. Several studies have shown that MPRIP is a potential drug target for a variety of diseases, including muscular dystrophy, cancer, and neurodegenerative diseases. For example, several studies have shown that MPRIP is a potential therapeutic target for muscular dystrophy, including a mouse model of Duchenne muscular dystrophy.

In addition to its potential as a drug target, MPRIP is also of interest as a biomarker for a variety of diseases. Several studies have shown that MPRIP is involved in the regulation of a variety of biological processes, including muscle contractions, cell survival, and inflammation. This suggests that MPRIP may be a useful biomarker for a variety of diseases.

In conclusion, MPRIP is a protein that is expressed in various tissues and cells throughout the body and is involved in a variety of biological processes, including muscle contractions and cell survival. Its role in these processes makes it a potential drug target or biomarker for a variety of diseases. Further research is needed to fully understand the functions of MPRIP and its potential as a therapeutic agent.

Protein Name: Myosin Phosphatase Rho Interacting Protein

Functions: Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells

The "MPRIP Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MPRIP comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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