Unlocking the Potential of MRPL45: A Drug Target and Biomarker for Mitochondrial Function

Target Name: MRPL45

NCBI ID: G84311

MRPL45

Unlocking the Potential of MRPL45: A Drug Target and Biomarker for Mitochondrial Function

Abstract:

Mitochondrial Ribosomal Protein L45 (MRPL45) is a protein that plays a crucial role in the structure and function of mitochondria, which are essential for energy metabolism. Mutations in the Mad Hatter's Protein (MRPL45) can cause a variety of neurological diseases , such as Alzheimer's disease, Parkinson's disease, etc. At the same time, it is also the target of many drugs, such as antidepressants, antipsychotics, and sleeping pills. This article aims to explore the potential role of MRPL45 in drug research and clinical applications and discuss its value as a biomarker.

1. Structure and function of MRPL45

MRPL45 is a protein with a molecular weight of 59.5 kDa and belongs to the Mitochondrial Ribosomal Protein family. The protein is composed of 924 amino acids, and its positioning sequence is A-H-L-K-L-L-I-L-H-F-Y-W-P-A-Q-E-R-S- T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F - Y - W - P - A - Q - E - R - S - T - F - Y - G - F - S - R - Y - H - F - T - E - D - K - L - I - L - H - F

Protein Name: Mitochondrial Ribosomal Protein L45

The "MRPL45 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MRPL45 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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