Target Name: MRPL37
NCBI ID: G51253
Review Report on MRPL37 Target / Biomarker Content of Review Report on MRPL37 Target / Biomarker
MRPL37
Other Name(s): 39S ribosomal protein L37, mitochondrial | ribosomal protein, mitochondrial, L2 | L2mt | Ribosomal protein, mitochondrial, L2 | RM37_HUMAN | MRP-L2 | L37mt | Mitochondrial large ribosomal subunit protein mL37 | MRPL37 variant 2 | 39S ribosomal protein L2, mitochondrial | MRP-L37 | 39S ribosomal protein L37, mitochondrial (isoform 2) | mitochondrial ribosomal protein L37 | RPML2 | MRPL2 | mitochondrial large ribosomal subunit protein mL37 | Mitochondrial ribosomal protein L37, transcript variant 2 | Mitochondrial ribosomal protein L37

Study of MRPL37: Potential Drug Targets and Biomarkers

Mitochondria are organelles that are responsible for generating energy in the form of ATP in cells throughout the body. They are also involved in the production of proteins, including Ribosomal Protein L37 (MRPL37), which is a key protein that is synthesized in the mitochondria. Unfortunately, MRPL37 has been associated with a number of diseases, including neurodegenerative disorders, cancer, and aging. As a result, it is of great interest to study the function of MRPL37 and to identify potential drug targets or biomarkers.

The Structure of MRPL37

MRPL37 is a 39S ribosomal protein that is synthesized in the mitochondria. It consists of 215 amino acids and has a molecular weight of 30.1 kDa. The protein has a characteristic Rossmann-fold structure, which is a type of alpha-helices that are composed of a series of amino acids that are arranged in a specific sequence. This structure is thought to play a role in the protein's stability and function.

The Expression and Localization of MRPL37

MRPL37 is expressed in a variety of tissues and cells throughout the body, including the brain, muscle, and blood cells. It is primarily localized to the mitochondria, where it is involved in the production of proteins. It is thought to be involved in the formation of organelles in the mitochondria, such as the mitochondrial protein matrix and the endoplasmic reticulum.

The Role of MRPL37 in Disease

MRPL37 has been associated with a number of diseases, including neurodegenerative disorders, cancer, and aging. It is thought to be involved in the development and progression of neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease. Studies have also shown that MRPL37 is involved in the development and progression of cancer, including leukemia and breast cancer. In addition, MRPL37 has been shown to be involved in aging, as it has been shown to be decreased in the brains of older mice.

Drug Targets for MRPL37

The potential drug targets for MRPL37 are vast and varied. One of the main targets is the production of MRPL37, which could be achieved by inhibiting the activity of the genes that encode for the protein. There are a number of potential drugs that have been shown to inhibit the production of MRPL37, including small molecules, peptides, and antibodies.

Another potential drug target for MRPL37 is its localization to the mitochondria. Mitochondria are involved in the production of energy, and the localization of MRPL37 to the mitochondria suggests that it may be involved in the production of energy. Drugs that inhibit the localization of MRPL37 to the mitochondria could be a potential treatment for a number of diseases, including neurodegenerative disorders and cancer.

Biomarkers for MRPL37

MRPL37 has been shown to be involved in a number of diseases, including neurodegenerative disorders, cancer, and aging. As a result, it may be a useful biomarker for these diseases. Studies have shown that the levels of MRPL37 are decreased in the brains of individuals with Alzheimer's disease and Parkinson's disease, and that the levels of MRPL37 are increased in the tumors of individuals with cancer. In addition, studies have shown that the levels of MRPL37 are decreased in the blood cells of individuals with neurodegenerative disorders.

Conclusion

MRPL37 is a protein that is synthesized in the mitochondria and is involved in the production of a number of proteins. It has been associated with a number of diseases, including neurodegenerative disorders, cancer, and aging. As a result, it is of great interest to study the function of MRPL37 and to identify potential drug targets or biomarkers. The potential drug targets for MRPL37 are vast and varied, including the production of MRPL37, its localization to the mitochondria, and its involvement in the

Protein Name: Mitochondrial Ribosomal Protein L37

The "MRPL37 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MRPL37 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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