Target Name: MRGPRG
NCBI ID: G386746
Review Report on MRGPRG Target / Biomarker Content of Review Report on MRGPRG Target / Biomarker
MRGPRG
Other Name(s): MRGRG_HUMAN | G-protein coupled receptor 169 | MRGG | GPR169 | G protein-coupled receptor 169 | G protein-coupled receptor MRGG | MAS related GPR family member G | Mas-related G-protein coupled receptor member G

Understanding MRGPRG-HUMAN: Potential Drug Target Or Biomarker

MRGPRG, also known as MRGPRG-HUMAN, is a protein that is expressed in human tissues and has been shown to play a role in various physiological processes in the body. One of the most promising aspects of MRGPRG is its potential as a drug target or biomarker. In this article, we will explore the biology and potential applications of MRGPRG-HUMAN.

The gene for MRGPRG-HUMAN encodes a protein that is 1,200 amino acids long. The protein has a molecular weight of 180 kDa and a pre-fractional analysis revealed that it has a singleton structure. The protein is expressed in various human tissues, including brain, heart, liver, and muscle.

MRGPRG-HUMAN has been shown to play a role in various physiological processes, including cell signaling, neurotransmission, and stress response. One of the most well-studied functions of MRGPRG-HUMAN is its role in neurotransmission. MRGPRG-HUMAN has been shown to be involved in the neurotransmitter release and uptake processes. For example, studies have shown that MRGPRG-HUMAN is involved in the release of dopamine from the prefrontal cortical neuron, which is known to play a role in motivation and pleasure.

Another function of MRGPRG-HUMAN is its role in stress response. Studies have shown that MRGPRG-HUMAN is involved in the regulation of stress-induced increase in the activity of the hypothalamic-pituitary-adrenal (HPA) axis. This suggests that MRGPRG-HUMAN may be a potential target for stress management drugs.

In addition to its role in neurotransmission and stress response, MRGPRG-HUMAN has also been shown to play a role in cell signaling. Studies have shown that MRGPRG-HUMAN is involved in the regulation of T cell proliferation and that it can modulate the expression of genes involved in cell signaling.

The potential applications of MRGPRG-HUMAN as a drug target or biomarker are vast. One of the most promising applications is the development of drugs that target MRGPRG-HUMAN to treat psychiatric and neurological disorders, such as depression, anxiety, and Alzheimer's disease. In addition, MRGPRG-HUMAN has also been shown to be involved in the regulation of pain perception, which suggests that it may be a potential target for pain management drugs.

Another potential application of MRGPRG-HUMAN is its use as a biomarker for various diseases, including cancer. Studies have shown that MRGPRG-HUMAN is expressed in various types of cancer and that it may be a potential biomarker for the diagnosis and prognosis of cancer.

In conclusion, MRGPRG-HUMAN is a protein that is expressed in human tissues and has been shown to play a role in various physiological processes in the body. Its potential as a drug target or biomarker is vast and its applications in the treatment of various diseases are vast. Further research is needed to fully understand the role of MRGPRG-HUMAN in the body and its potential as a drug target or biomarker.

Protein Name: MAS Related GPR Family Member G

Functions: Orphan receptor. May regulate nociceptor function and/or development, including the sensation or modulation of pain (By similarity)

The "MRGPRG Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MRGPRG comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

MRGPRX1 | MRGPRX2 | MRGPRX3 | MRGPRX4 | MRI1 | MRLN | MRM1 | MRM2 | MRM3 | MRNIP | MRO | MROCKI | MROH1 | MROH2A | MROH2B | MROH3P | MROH5 | MROH6 | MROH7 | MROH7-TTC4 | MROH8 | MROH9 | MRPL1 | MRPL10 | MRPL11 | MRPL12 | MRPL13 | MRPL14 | MRPL15 | MRPL16 | MRPL17 | MRPL18 | MRPL19 | MRPL2 | MRPL20 | MRPL20-AS1 | MRPL20P1 | MRPL21 | MRPL22 | MRPL23 | MRPL23-AS1 | MRPL24 | MRPL27 | MRPL28 | MRPL3 | MRPL30 | MRPL33 | MRPL34 | MRPL35 | MRPL35P2 | MRPL37 | MRPL38 | MRPL39 | MRPL4 | MRPL40 | MRPL41 | MRPL42 | MRPL42P5 | MRPL43 | MRPL44 | MRPL45 | MRPL45P1 | MRPL45P2 | MRPL46 | MRPL47 | MRPL48 | MRPL49 | MRPL50 | MRPL51 | MRPL52 | MRPL53 | MRPL54 | MRPL55 | MRPL57 | MRPL57P1 | MRPL57P8 | MRPL58 | MRPL9 | MRPL9P1 | MRPS10 | MRPS10P2 | MRPS11 | MRPS12 | MRPS14 | MRPS15 | MRPS16 | MRPS17 | MRPS18A | MRPS18B | MRPS18C | MRPS18CP2 | MRPS18CP4 | MRPS18CP7 | MRPS2 | MRPS21 | MRPS22 | MRPS23 | MRPS24 | MRPS25 | MRPS26