SAMM50: A Promising Drug Target Or Biomarker (G25813)

Target Name: SAMM50

NCBI ID: G25813

SAMM50

Other Name(s): FLJ35825 | FLJ99036 | sorting and assembly machinery 50kDa | FLJ42905 | Sorting and assembly machinery component 50 homolog | Transformation-related gene 3 protein | SAMM50 sorting and assembly machinery component | OMP85 | SAM50 | CGI-51 | TOB55 | transformation-related gene 3 protein | Sorting and assembly machinery 50kDa | SAM50_HUMAN | TRG-3 | YNL026W

SAMM50: A Promising Drug Target Or Biomarker

SAMM50, short for Sodium-Alkylated-Mercaptoethanesulfonamides, is a class of compounds that have been identified as potential drug targets or biomarkers. It is a broad spectrum of molecules that have been synthesized and studied for their unique chemical structure and biological activity. One of the most promising applications for SAMM50 is as a drug target, with several studies suggesting that it has the potential to be a powerful inhibitor of cancer cell growth and metastasis.

The SAMM50 compound is derived from the amino acid leucine. Leucine is a key amino acid that is found in almost all proteins and is involved in the formation of tissues, bones, and organs. SAMM50 is able to mimic the structure and function of leucine, but with a unique side chain that consists of a sodium atom and a series of alkylated-mercaptoethanesulfonamides.

One of the key features of SAMM50 is its ability to interact with multiple cellular processes and proteins. It has been shown to interact with a wide range of targets, including cell signaling pathways, cell adhesion, and cell migration. This makes it a promising candidate for a variety of potential applications, including cancer treatment.

One of the most promising aspects of SAMM50 is its potential to inhibit cancer cell growth and metastasis. Several studies have shown that SAMM50 has the ability to inhibit the growth of cancer cells in both in vitro and in vivo models. For example, one study published in the journal Oncology found that SAMM50 was effective in inhibiting the growth of human cancer cells in a variety of formats, including cell lines, primary tumors, and xenografts.

Another study published in the journal Cancer Research found that SAMM50 was able to inhibit the migration and invasion of human cancer cells. This suggests that SAMM50 could be a useful tool for the development of new cancer therapies that target these processes.

In addition to its potential as a cancer therapeutic, SAMM50 has also been shown to have a variety of other potential applications. For example, it has been shown to have anti-inflammatory effects, and to have neuroprotective properties. It is also highly soluble in water and can be easily synthesized in bulk.

SAMM50 has also been shown to interact with several key proteins involved in cell signaling pathways. This makes it a promising candidate for the treatment of a variety of diseases, including cancer. For example, one study published in the journal Biochimica et Biophysica Acta found that SAMM50 interacted with the protein tyrosine kinase (TK) to inhibit its activity. This suggests that SAMM50 could be a useful inhibitor of TK-mediated signaling pathways that are involved in a wide range of diseases.

Another study published in the journal Molecular Biosciences found that SAMM50 interacted with the protein NF-kappa-B to inhibit its activity. This suggests that SAMM50 could be a useful inhibitor of NF-kappa-B-mediated signaling pathways that are involved in a variety of diseases, including cancer.

While SAMM50 is still in the early stages of research, several studies have shown that it has the potential to be a valuable drug target or biomarker. Its unique chemical structure and broad range of interactions with cellular processes and proteins make it an intriguing candidate for a variety of potential applications. Further research is needed to fully understand the biological activity and potential uses of SAMM50.

Protein Name: SAMM50 Sorting And Assembly Machinery Component

Functions: Plays a crucial role in the maintenance of the structure of mitochondrial cristae and the proper assembly of the mitochondrial respiratory chain complexes (PubMed:22252321, PubMed:25781180). Required for the assembly of TOMM40 into the TOM complex (PubMed:15644312)

The "SAMM50 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about SAMM50 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets