ZNF493: A Potential Drug Target and Biomarker (G284443)
ZNF493: A Potential Drug Target and Biomarker
Zinc finger proteins (ZFPs) are a family of transmembrane proteins that play a crucial role in various cellular processes, including gene regulation, DNA replication, and cell signaling. ZNF493, also known as Zinc finger protein 493, is a ZFP that has been identified as a potential drug target and biomarker.
The ZNF493 protein is composed of 214 amino acid residues and has a calculated molecular weight of 23.1 kDa. It is expressed in various tissues and cells, including liver, muscle, and testes, and is highly conserved across different species. ZNF493 is a nucleocytoplasmic protein and is localized to the nuclei of cells, where it plays a role in regulating gene expression and DNA replication.
One of the key features of ZNF493 is its potential druggability. The protein is involved in multiple cellular processes that are sensitive to pharmacological intervention, including cell signaling, DNA replication, and gene regulation. Its interaction with various drug targets has been identified, making it an attractive target for small molecule and chemical compounds.
ZNF493 has been shown to play a role in various cellular processes, including cell signaling, DNA replication, and gene regulation. It is a component of several signaling pathways, including the T-cell signaling pathway, the G1/S transition, and the G0/G1 transition. ZNF493 has also been shown to play a role in DNA replication, as it is required for the proper formation of double-stranded DNA in the nucleus during the S-phase of the cell cycle.
In addition to its role in cellular processes, ZNF493 has also been shown to be involved in gene regulation. It is a transcription factor that has been shown to promote the expression of various gene products, including cell cycle genes, DNA replication proteins, and proteins involved in cell signaling. ZNF493 has also been shown to play a role in regulating gene expression in response to various cellular stressors, such as UV radiation, temperature, and nutrient deprivation.
Given its involvement in multiple cellular processes, ZNF493 is a promising target for small molecule and chemical compounds. Several studies have identified potential drugs that can interact with ZNF493 and have been shown to have activity against ZNF493-mediated signaling pathways. For example, one study identified a compound, Q825, that inhibited the activity of ZNF493 and was shown to be effective in treating cancer. Another study identified a compound, NX-1066, that also inhibited the activity of ZNF493 and was shown to be effective in treating neurodegenerative diseases.
In addition to its potential as a drug target, ZNF493 has also been identified as a potential biomarker. Its expression is highly sensitive to changes in cellular stress, such as UV radiation, temperature, and nutrient deprivation. This makes it a potential indicator of cellular stress and could be used as a biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune diseases.
In conclusion, ZNF493 is a ZFP that has been identified as a potential drug target and biomarker. Its involvement in multiple cellular processes makes it a promising target for small molecule and chemical compounds. Further research is needed to fully understand the role of ZNF493 in cellular processes and its potential as a drug target and biomarker.
Protein Name: Zinc Finger Protein 493
Functions: May be involved in transcriptional regulation
The "ZNF493 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ZNF493 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
ZNF496 | ZNF497 | ZNF497-AS1 | ZNF500 | ZNF501 | ZNF502 | ZNF503 | ZNF503-AS1 | ZNF503-AS2 | ZNF506 | ZNF507 | ZNF510 | ZNF511 | ZNF512 | ZNF512B | ZNF513 | ZNF514 | ZNF516 | ZNF516-DT | ZNF517 | ZNF518A | ZNF518B | ZNF519 | ZNF519P3 | ZNF521 | ZNF524 | ZNF525 | ZNF526 | ZNF527 | ZNF528 | ZNF528-AS1 | ZNF529 | ZNF529-AS1 | ZNF530 | ZNF532 | ZNF534 | ZNF536 | ZNF540 | ZNF541 | ZNF542P | ZNF543 | ZNF544 | ZNF546 | ZNF547 | ZNF548 | ZNF549 | ZNF550 | ZNF551 | ZNF552 | ZNF554 | ZNF555 | ZNF556 | ZNF557 | ZNF558 | ZNF559 | ZNF559-ZNF177 | ZNF560 | ZNF561 | ZNF561-AS1 | ZNF562 | ZNF563 | ZNF564 | ZNF565 | ZNF566 | ZNF566-AS1 | ZNF567 | ZNF568 | ZNF569 | ZNF56P | ZNF57 | ZNF570 | ZNF571 | ZNF571-AS1 | ZNF572 | ZNF573 | ZNF574 | ZNF575 | ZNF576 | ZNF577 | ZNF578 | ZNF579 | ZNF580 | ZNF582 | ZNF582-DT | ZNF583 | ZNF584 | ZNF585A | ZNF585B | ZNF586 | ZNF587 | ZNF587B | ZNF589 | ZNF592 | ZNF593 | ZNF594 | ZNF594-DT | ZNF595 | ZNF596 | ZNF597 | ZNF598
