LCE1D: A Potential Drug Target for Neurological Disorders (G353134)

Target Name: LCE1D

NCBI ID: G353134

LCE1D

LCE1D: A Potential Drug Target for Neurological Disorders

LCE1D (Leucine-rich repeat-containing 1 protein) is a protein that is expressed in various tissues of the body, including the brain. It is characterized by the presence of a unique repeat sequence, known as a leucine-rich repeat, which is composed of the amino acids leucine, isoleucine, and valine.

Recent studies have identified LCE1D as a potential drug target for various neurological and psychiatric disorders, including Alzheimer's disease, Parkinson's disease, and depression. This is due to the fact that LCE1D is involved in the regulation of several important cellular processes, including the development and progression of nerve cells, neurotrophin signaling, and inflammation.

One of the key functions of LCE1D is its role in the regulation of neurotrophin signaling. Neurotrophins are a family of proteins that play a critical role in the survival and growth of nerve cells, and are involved in the development and progression of neurodegenerative diseases. LCE1D has been shown to play a role in the regulation of neurotrophin signaling by interacting with the protein TrkB, which is a key regulator of neurotrophin signaling.

In addition to its role in neurotrophin signaling, LCE1D is also involved in the regulation of inflammation. Chronic inflammation has been associated with a number of diseases, including neurodegenerative diseases, and LCE1D has been shown to play a role in the regulation of inflammation by interacting with the protein NF-kappa-B.

The unique repeat sequences present in LCE1D make it a promising target for drug development. Studies have shown that LCE1D can be effectively targeted by small molecules, such as those that bind to specific repeats or the core region of the protein. In addition, LCE1D is also a good candidate for a protein-based vaccine, as its repetitive structure makes it easier to generate antibodies that recognize the protein.

Overall, LCE1D is a protein that has great potential as a drug target or biomarker for the treatment of neurological and psychiatric disorders. Further research is needed to fully understand the role of LCE1D in the regulation of cellular processes and its potential as a therapeutic target.

Protein Name: Late Cornified Envelope 1D

Functions: Precursors of the cornified envelope of the stratum corneum

The "LCE1D Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LCE1D comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets