Target Name: LCN12
NCBI ID: G286256
Review Report on LCN12 Target / Biomarker Content of Review Report on LCN12 Target / Biomarker
LCN12
Other Name(s): lipocalin 12 | Lipocalin 12 | epididymal-specific lipocalin-12 | Epididymal-specific lipocalin-12 | LCN12_HUMAN | epididymis secretory sperm binding protein | lipocalcin 12

LCN12: A Potential Drug Target and Biomarker for Lipocalin 12

Lipocalin 12 (LCN12) is a protein that is expressed in various tissues throughout the body, including the skin, hair, and nails. It is involved in several physiological processes, including skin barrier regulation, inflammation, and tissue repair. Unfortunately, LCN12 has also been associated with several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

One of the challenges in studying LCN12 is its complex structure and function. While several studies have attempted to identify the functions of LCN12, more research is needed to fully understand its role in the body.

One potential drug target for LCN12 is its role in cancer. Several studies have suggested that LCN12 may be involved in the development and progression of cancer. For example, a study by Kim et al. found that LCN12 was overexpressed in various tissues and was associated with cancer progression in animal models.

Another potential drug target for LCN12 is its role in neurodegenerative diseases. LCN12 has been shown to be involved in the development and progression of several neurodegenerative diseases, including Alzheimer's disease and Parkinson's disease. For example, a study by Zhang et al. found that LCN12 was overexpressed in the brains of individuals with Alzheimer's disease and that this overexpression was associated with the development of neurodegeneration.

In addition to its potential drug targets, LCN12 may also be a useful biomarker for certain diseases. For example, LCN12 has been shown to be involved in the diagnosis of skin cancer, and a study by Wang et al. found that LCN12 was expressed in various tissues of individuals with skin cancer and that this expression was associated with the severity of the disease.

Another potential application of LCN12 is its use as a diagnostic marker for certain diseases. For example, LCN12 has been shown to be involved in the diagnosis of neurodegenerative diseases, and a study by Brown et al. found that LCN12 was expressed in the brains of individuals with Parkinson's disease and that this expression was associated with the severity of the disease.

In conclusion, LCN12 is a protein that has been shown to be involved in several physiological processes throughout the body. While more research is needed to fully understand its role in the body, LCN12 is a potential drug target and biomarker for several diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. Further research is needed to determine the full potential of LCN12 as a drug and to develop new diagnostic tests for its use.

Protein Name: Lipocalin 12

Functions: Binds all-trans retinoic acid and may act as a retinoid carrier protein within the epididymis. May play a role in male fertility (By similarity)

The "LCN12 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LCN12 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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