Target Name: LIF
NCBI ID: G3976
Review Report on LIF Target / Biomarker Content of Review Report on LIF Target / Biomarker
LIF
Other Name(s): Melanoma-derived LPL inhibitor | CDF | Leukemia inhibitory factor (cholinergic differentiation factor) | melanoma-derived LPL inhibitor | Human interleukin in DA cells | LIF variant 2 | MLPLI | D factor | Differentiation inhibitory activity | hepatocyte-stimulating factor III | Leukemia inhibitory factor (isoform 1) | Cholinergic differentiation factor | Differentiation-inducing factor | LIF interleukin 6 family cytokine, transcript variant 1 | human interleukin in DA cells | Hepatocyte-stimulating factor III | Leukemia inhibitory factor (isoform 2) | LIF interleukin 6 family cytokine | DIA | LIF interleukin 6 family cytokine, transcript variant 2 | LIF_HUMAN | Differentiation-stimulating factor | Leukemia inhibitory factor | LIF variant 1 | cholinergic differentiation factor | differentiation inhibitory activity | differentiation-inducing factor | differentiation-stimulating factor | Emfilermin | HILDA

LIF Inhibitors: A Promising New Type of Cancer Treatment

LIF (Leucine-rich repeat-containing) inhibitors are a type of drug that is being studied for their potential to treat melanoma, a type of skin cancer that is the most common form of cancer in the United States. LIF inhibitors are designed to target the LIF protein, which is a protein that is found in the cells of many different types of cells in the body.

The LIF protein is involved in many different processes in the body, including cell growth, differentiation, and survival. It is also involved in the development and progression of cancer. Some studies have suggested that LIF may be a potential drug target for cancer because it is involved in the growth and survival of many different types of cancer cells.

One of the reasons why LIF inhibitors may be a good candidate for cancer treatment is that they can selectively target the LIF protein in cancer cells, rather than all of the cells in the body. This can help to reduce the potential side effects of the drug, because the drug will not affect the normal functioning of all of the cells in the body.

Another potential advantage of LIF inhibitors is that they can be easily modified to target different subtypes of LIF. This can help to increase the diversity of the drugs that are available for cancer treatment.

In addition to their potential as a cancer treatment, LIF inhibitors have also been studied for their potential as a biomarker. A biomarker is a substance that is produced by the body that can be used as a sign of the presence of a particular disease or condition. Some studies have suggested that LIF inhibitors may be able to serve as a biomarker for cancer, because they can be easily detected in the body and can be used to diagnose and monitor the progress of the disease.

Overall, LIF inhibitors are a promising new class of drugs that are being studied for their potential to treat cancer. While more research is needed to fully understand the effects of these drugs, they have the potential to be a valuable tool in the fight against cancer.

Protein Name: LIF Interleukin 6 Family Cytokine

Functions: LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes

The "LIF Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about LIF comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

LIFR | LIFR-AS1 | LIG1 | LIG3 | LIG4 | LILRA1 | LILRA2 | LILRA3 | LILRA4 | LILRA5 | LILRA6 | LILRB1 | LILRB2 | LILRB3 | LILRB4 | LILRB5 | LILRP1 | LILRP2 | LIM domain kinase (LIMK) | LIM2 | LIMA1 | LIMASI | LIMCH1 | LIMD1 | LIMD1-AS1 | LIMD2 | LIME1 | LIMK1 | LIMK2 | LIMS1 | LIMS2 | LIMS3 | LIMS3-LOC440895 | LIMS4 | LIN28A | LIN28B | LIN28B-AS1 | LIN37 | LIN52 | LIN54 | LIN7A | LIN7B | LIN7C | LIN9 | LINC-PINT | LINC-ROR | LINC00028 | LINC00029 | LINC00032 | LINC00051 | LINC00052 | LINC00092 | LINC00102 | LINC00106 | LINC00111 | LINC00112 | LINC00113 | LINC00114 | LINC00115 | LINC00158 | LINC00159 | LINC00160 | LINC00161 | LINC00163 | LINC00173 | LINC00174 | LINC00184 | LINC00189 | LINC00200 | LINC00205 | LINC00207 | LINC00208 | LINC00210 | LINC00221 | LINC00222 | LINC00226 | LINC00235 | LINC00239 | LINC00240 | LINC00242 | LINC00243 | LINC00244 | LINC00251 | LINC00260 | LINC00261 | LINC00265 | LINC00266-1 | LINC00266-3 | LINC00272 | LINC00273 | LINC00276 | LINC00278 | LINC00293 | LINC00294 | LINC00298 | LINC00299 | LINC00301 | LINC00303 | LINC00304 | LINC00305