MIR194-1: A Promising Drug Target and Biomarker for Cancer (G406969)
MIR194-1: A Promising Drug Target and Biomarker for Cancer
MicroRNA (miRNA) 194-1, also known as MIR194-1, is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer. MIR194-1 is a key regulator of gene expression in many organisms, and its levels have been shown to be altered in a wide range of diseases, including cancer.
The miRNA pathway is a complex system of small non-coding RNAs that play a critical role in post-transcriptional gene regulation. MiRNAs are derived from mRNAs by a process called splicing, and they are typically loaded onto RNA-protein machines, also known as ribosome binding proteins (RBP), to form a complex called a microRNA-ribonucleoprotein (miRNA-RNP) complex. This complex interacts with the host cell's RNA machinery to target specific mRNAs for degradation or translation into protein.
MIR194-1 is a member of the miRNA-RNP complex and has been shown to play a role in regulating gene expression in various organisms, including humans. MIR194-1 has been shown to regulate the expression of target genes that are involved in cell growth, apoptosis, and inflammation.
One of the most promising aspects of MIR194-1 is its potential as a drug target. MIR194-1 has been shown to interact with several protein partners, including the transcription factor E2F1, which plays a critical role in driving the growth and survival of cancer cells. By inhibiting the activity of E2F1, MIR194-1 has been shown to reduce the growth and survival of cancer cells in cell culture and animal models.
In addition to its potential as a drug target, MIR194-1 has also been shown to be a valuable biomarker for cancer. The levels of MIR194-1 have been shown to be altered in a wide range of cancer types, including breast, ovarian, and colorectal cancers. Additionally, studies have shown that MIR194-1 can be used as a biomarker to predict the outcome of cancer surgery, as well as to identify patients who are at high risk for recurrence.
MIR194-1 is also a potential biomarker for other diseases, including cardiovascular disease and neurodegenerative diseases. The altered levels of MIR194-1 have been observed in a wide range of tissues and biological processes in these diseases, and studies are underway to determine its potential as a diagnostic or therapeutic target.
In conclusion, MIR194-1 is a promising drug target and biomarker for a wide range of diseases. Its ability to regulate gene expression and interact with protein partners makes it an attractive candidate for drug development, as well as for use as a biomarker for disease diagnosis and prognosis. Further research is needed to fully understand the role of MIR194-1 in these processes and to determine its potential as a therapeutic intervention.
Protein Name: MicroRNA 194-1
The "MIR194-1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about MIR194-1 comprehensively, including but not limited to:
• general information;
• protein structure and compound binding;
• protein biological mechanisms;
• its importance;
• the target screening and validation;
• expression level;
• disease relevance;
• drug resistance;
• related combination drugs;
• pharmacochemistry experiments;
• related patent analysis;
• advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai
More Common Targets
MIR194-2 | MIR194-2HG | MIR195 | MIR196A1 | MIR196A2 | MIR196B | MIR197 | MIR1972-1 | MIR1972-2 | MIR1973 | MIR1976 | MIR198 | MIR199A1 | MIR199A2 | MIR199B | MIR19A | MIR19B1 | MIR19B2 | MIR200A | MIR200B | MIR200C | MIR200CHG | MIR202 | MIR202HG | MIR203A | MIR203B | MIR204 | MIR205 | MIR2052 | MIR2052HG | MIR2053 | MIR2054 | MIR205HG | MIR206 | MIR208A | MIR208B | MIR20A | MIR20B | MIR21 | MIR210 | MIR210HG | MIR211 | MIR2110 | MIR2113 | MIR2114 | MIR2115 | MIR2116 | MIR2117 | MIR212 | MIR214 | MIR215 | MIR216A | MIR216B | MIR217 | MIR217HG | MIR218-1 | MIR218-2 | MIR219A1 | MIR219A2 | MIR219B | MIR22 | MIR221 | MIR222 | MIR223 | MIR224 | MIR2276 | MIR2277 | MIR2278 | MIR22HG | MIR2355 | MIR2392 | MIR23A | MIR23AHG | MIR23B | MIR23C | MIR24-1 | MIR24-2 | MIR2467 | MIR25 | MIR2681 | MIR2682 | MIR26A1 | MIR26A2 | MIR26B | MIR27A | MIR27B | MIR28 | MIR2861 | MIR2909 | MIR296 | MIR297 | MIR298 | MIR299 | MIR29A | MIR29B1 | MIR29B2 | MIR29B2CHG | MIR29C | MIR300 | MIR301A
