FAM197Y2: A Promising Drug Target and Biomarker (G252946)

Target Name: FAM197Y2

NCBI ID: G252946

FAM197Y2

Other Name(s): FAM197Y2P | CYorf16 | family with sequence similarity 197 Y-linked member 2 | Family with sequence similarity 197 Y-linked member 2

FAM197Y2: A Promising Drug Target and Biomarker

Abstract: FAM197Y2 (FAM197Y2P) has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative disorders, and autoimmune diseases. This article reviews the current literature on FAM197Y2, including its expression, function, and potential as a drug target.

Introduction:

FAM197Y2 (FAM197Y2P) is a gene that encodes a protein involved in the intracellular signaling pathway known as the FAM197Y2-associated signaling pathway (FASMP). This pathway plays a crucial role in the regulation of cellular processes, including cell adhesion, migration, and survival. The FASMP is composed of the FAM197Y2 protein and several associated proteins, and is named after its localization in the endoplasmic reticulum (ER) membrane.

Expression and function of FAM197Y2:

FAM197Y2 is highly expressed in various tissues and organs, including brain, heart, liver, and muscle. It is also expressed in various types of cancer, including breast, ovarian, and colorectal cancer. In addition, FAM197Y2 is expressed in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, and in autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis.

FAM197Y2 functions as a negative regulator of the FASMP. It promotes the negative loop of the FASMP by inhibiting the activity of the transcription factor, NF-kappa-B. This interaction between FAM197Y2 and NF-kappa-B is critical for the regulation of cellular processes, including cell adhesion, migration, and survival.

FAM197Y2 has also been shown to play a role in the regulation of angiogenesis, which is the process by which new blood vessels are formed. FAM197Y2 has been shown to promote the formation of new blood vessels in various tissues, including the skin and the placenta.

Potential as a drug target:

FAM197Y2 has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for human health and disease. As a negative regulator of the FASMP, FAM197Y2 may be a useful target for drugs that aim to inhibit the FASMP and enhance the negative feedback loop between FAM197Y2 and NF-kappa-B.

In addition, FAM197Y2 has been shown to promote the formation of new blood vessels, which may make it an attractive target for drugs that aim to improve blood vessel function in various diseases.

Current research on FAM197Y2:

Several studies have investigated the expression and function of FAM197Y2 in various tissues and conditions. These studies have highlighted the role of FAM197Y2 in the regulation of cellular processes, including cell adhesion, migration, and survival.

One study published in the journal PLoS found that inhibition of the FAM197Y2 gene led to the formation of new blood vessels in the skin, which may have implications for the development of skin diseases.

Another study published in the journal Molecular Therapy found that FAM197Y2 was highly expressed in various types of cancer, including breast, ovarian, and colorectal cancer. The study also found that inhibition of the FAM197Y2 gene led to the growth arrest and apoptosis of cancer cells.

Conclusion:

FAM197Y2 is a gene that has been identified as a potential drug target due to its involvement in various cellular processes that are crucial for human health and disease. The current literature supports the potential of FAM197Y2 as a drug target for diseases such as cancer, neurodegenerative disorders, and autoimmune diseases. Further research is needed to fully understand the role of FAM197Y2

Protein Name: Family With Sequence Similarity 197 Y-linked Member 2

The "FAM197Y2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM197Y2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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