FAM200A: A Potential Drug Target and Biomarker (G221786)

Target Name: FAM200A

NCBI ID: G221786

FAM200A

FAM200A: A Potential Drug Target and Biomarker

The FAM200A protein is a potential drug target and biomarker that has been identified in various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders. FAM200A is a member of the FAM family of proteins, which are involved in various cellular processes, including DNA replication, gene expression, and cellular signaling.

The FAM200A protein is a 200-kDa transmembrane protein that is expressed in various tissues and cells, including the brain, pancreas, and blood cells. It is characterized by a N-terminal transmembrane domain, a cytoplasmic tail, and a single intracellular loop. The FAM200A protein is involved in various cellular processes, including cell signaling, DNA replication, and gene expression.

One of the unique features of the FAM200A protein is its ability to interact with various signaling pathways, including TGF-β, NF-kappa-B, and PI3K/AKT signaling pathways. This interactivity suggests that the FAM200A protein may play a role in various cellular processes, including cell signaling and survival.

FAM200A has also been shown to be involved in the regulation of cellular replication and gene expression. For example, studies have shown that the FAM200A protein can interact with the transcription factor, p21, and enhance its ability to bind to DNA. This interaction suggests that the FAM200A protein may play a role in the regulation of gene expression, including the expression of genes involved in cancer progression.

In addition to its role in cell signaling and replication, the FAM200A protein is also involved in the regulation of cellular stress responses. Studies have shown that the FAM200A protein can interact with the protein, heat shock factor (HSF), and enhance its ability to promote cellular stress responses. This interaction suggests that the FAM200A protein may play a role in the regulation of cellular stress responses, including the stress responses that occur in neurodegenerative diseases.

The FAM200A protein is also involved in the regulation of cellular adhesion. Studies have shown that the FAM200A protein can interact with the protein, cadherin, and enhance its ability to promote cellular adhesion. This interaction suggests that the FAM200A protein may play a role in the regulation of cellular adhesion, including the regulation of tissue repair and regeneration.

In addition to its role in cell signaling and regulation, the FAM200A protein is also involved in the regulation of cellular aging. Studies have shown that the FAM200A protein can interact with the protein, p53 and enhance its ability to promote cellular aging. This interaction suggests that the FAM200A protein may play a role in the regulation of cellular aging, including the aging of brain cells.

Overall, the FAM200A protein is a potential drug target and biomarker that has been shown to be involved in various cellular processes, including cell signaling, DNA replication, gene expression, stress responses, and cellular aging. Further research is needed to fully understand the role of the FAM200A protein in these processes and its potential as a drug target.

Protein Name: Family With Sequence Similarity 200 Member A

The "FAM200A Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about FAM200A comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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