Target Name: ROR2
NCBI ID: G4920
Review Report on ROR2 Target / Biomarker Content of Review Report on ROR2 Target / Biomarker
ROR2
Other Name(s): NTRKR2 | BDB | receptor tyrosine kinase like orphan receptor 2 | ROR2_HUMAN | Tyrosine-protein kinase transmembrane receptor ROR2 (isoform 1) | neurotrophic tyrosine kinase receptor-related 2 | BDB1 | Receptor tyrosine kinase like orphan receptor 2, transcript variant 1 | Neurotrophic tyrosine kinase, receptor-related 2 | Tyrosine-protein kinase transmembrane receptor ROR2 | ROR2 variant 1

ROR2: A Non-Coding RNA Molecule with Potential as A Drug Target Or Biomarker

ROR2 (Reverse Open Reading Frame 2) is a non-coding RNA molecule that has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. Its unique structure and function have made it an attractive target for researchers to investigate, and recent studies have shed light on its potential role in these fields.

ROR2 is a non-coding RNA molecule that is approximately 200 nucleotides in length. It is expressed in a variety of tissues and cells in the body and is involved in the regulation of gene expression. ROR2 is highly conserved across different species, which suggests that it plays a critical role in the functioning of RNA molecules.

One of the key features of ROR2 is its ability to interact with protein-coding genes. This interaction is known as RNA-protein interactions and is a crucial process in gene regulation. ROR2 has been shown to interact with various protein-coding genes, including factors that regulate cell growth, apoptosis, and inflammation. This interaction between ROR2 and protein-coding genes raises the possibility that ROR2 may be a drug target or biomarker for diseases that are characterized by the disruption of normal gene regulation.

In addition to its role in gene regulation, ROR2 has also been shown to play a role in the regulation of cellular processes that are important for overall health and disease. For example, ROR2 has been shown to be involved in the regulation of cell adhesion, which is important for the development and maintenance of tissues and organs. ROR2 has also been shown to be involved in the regulation of cell migration, which is important for the formation of tissues and organs during development and for the maintenance of tissues and organs during adulthood.

The potential role of ROR2 as a drug target or biomarker for diseases is an area of active research. Several studies have investigated the potential targets of ROR2 and have identified potential therapeutic approaches. For example, researchers have shown that inhibiting ROR2 can lead to the growth arrest and apoptosis in cancer cells. This suggests that ROR2 may be an effective target for cancer therapies. In addition, ROR2 has been shown to be involved in the regulation of neurodegenerative diseases, which suggests that it may be an effective target for therapies that are aimed at treating these conditions.

Another promising aspect of ROR2 research is its potential as a biomarker for disease diagnosis and monitoring. Several studies have shown that ROR2 can be used as a potential biomarker for various diseases, including cancer, neurodegenerative diseases, and psychiatric disorders. For example, researchers have shown that ROR2 levels can be used as a diagnostic marker for cancer and that they can also be used to monitor the effectiveness of cancer therapies.

In conclusion, ROR2 is a non-coding RNA molecule that has the potential to be a drug target or biomarker for various diseases. Its unique structure and function as a regulator of gene expression and cellular processes make it an attractive target for researchers to investigate. Further studies are needed to fully understand the role of ROR2 in disease and to develop effective therapies that target it.

Protein Name: Receptor Tyrosine Kinase Like Orphan Receptor 2

Functions: Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development (By similarity). Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation (PubMed:17717073). In contrast, has also been shown to have very little tyrosine kinase activity in vitro. May act as a receptor for wnt ligand WNT5A which may result in the inhibition of WNT3A-mediated signaling (PubMed:25029443)

The "ROR2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ROR2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

RORA | RORA-AS1 | RORB | RORC | ROS1 | Roundabout homolog receptor | RP1 | RP1L1 | RP2 | RP9 | RP9P | RPA1 | RPA2 | RPA3 | RPA3P1 | RPA4 | RPAIN | RPAP1 | RPAP2 | RPAP3 | RPAP3-DT | RPE | RPE65 | RPEL1 | RPF1 | RPF2 | RPGR | RPGRIP1 | RPGRIP1L | RPH3A | RPH3AL | RPH3AL-AS1 | RPIA | RPL10 | RPL10A | RPL10AP10 | RPL10AP12 | RPL10AP3 | RPL10AP6 | RPL10AP7 | RPL10AP9 | RPL10L | RPL10P13 | RPL10P16 | RPL10P2 | RPL10P4 | RPL10P6 | RPL10P9 | RPL11 | RPL11P4 | RPL12 | RPL12P32 | RPL12P38 | RPL12P6 | RPL12P7 | RPL13 | RPL13A | RPL13AP16 | RPL13AP17 | RPL13AP20 | RPL13AP22 | RPL13AP23 | RPL13AP25 | RPL13AP3 | RPL13AP5 | RPL13AP6 | RPL13AP7 | RPL13P12 | RPL13P5 | RPL13P6 | RPL14 | RPL14P1 | RPL14P3 | RPL15 | RPL15P11 | RPL15P20 | RPL15P21 | RPL15P22 | RPL15P3 | RPL15P4 | RPL17 | RPL17P25 | RPL17P33 | RPL17P34 | RPL17P39 | RPL17P4 | RPL17P44 | RPL17P49 | RPL17P7 | RPL17P8 | RPL18 | RPL18A | RPL18AP16 | RPL18AP3 | RPL18AP6 | RPL18AP8 | RPL18P1 | RPL18P13 | RPL18P4 | RPL19