Target Name: OSM
NCBI ID: G5008
Review Report on OSM Target / Biomarker Content of Review Report on OSM Target / Biomarker
OSM
Other Name(s): Oncostatin-M (isoform 1) | OSM variant 1 | ONCM_HUMAN | oncostatin M | Oncostatin M, transcript variant 1 | Oncostatin-M

OSM: A Key Regulator of Cell Growth and Differentiation

OSM, or Oncostatin-M, is a protein that is expressed in various tissues throughout the body. It is a key regulator of cell growth and differentiation, and has been identified as a potential drug target for various diseases. In this article, we will explore the biology of OSM and its potential as a drug target.

The Oncostatin-M protein is a member of the transforming growth factor beta (TGF-β) family, which is a well-known regulator of cell growth and differentiation. TGF-β signaling is involved in many important cellular processes, including cell proliferation, migration, and angiogenesis. OSM is a critical component of the TGF-β signaling pathway, and plays a key role in regulating cell proliferation and differentiation.

OSM is expressed in a variety of tissues throughout the body, including the liver, pancreas, and gastrointestinal tract. It is highly expressed in the liver, and is also expressed in the pancreas and gastrointestinal tract. The pancreas is a gland that produces insulin, a hormone that regulates blood sugar levels. The gastrointestinal tract is the channel through which food is ingested and digested. OSM is expressed in all of these tissues, which suggests that it plays an important role in the regulation of these processes.

OSM is involved in many important cellular processes that are critical for the development and maintenance of tissues. It is involved in the regulation of cell proliferation, cell differentiation, and cell-cell adhesion. It is also involved in the regulation of angiogenesis, the formation of new blood vessels. OSM is a key regulator of the TGF-β signaling pathway, and is involved in the regulation of many cellular processes that are critical for the development and maintenance of tissues.

OSM is a potential drug target for several diseases. For example, it is a known regulator of the development and maintenance of cancer, and is involved in the regulation of cell proliferation. OSM is also involved in the regulation of the development and maintenance of autoimmune diseases, such as rheumatoid arthritis and multiple sclerosis. OSM is involved in the regulation of the development and maintenance of diseases that affect the gastrointestinal tract, such as inflammatory bowel disease and colorectal cancer.

OSM is a potential drug target for several diseases because of its involvement in the regulation of many important cellular processes that are critical for the development and maintenance of tissues. It is a key regulator of the TGF-β signaling pathway, and is involved in the regulation of cell proliferation, cell differentiation, and cell-cell adhesion. OSM is a potential drug target for diseases that are characterized by the regulation of these processes, including cancer, autoimmune diseases, and diseases of the gastrointestinal tract.

In conclusion, OSM is a protein that is expressed in various tissues throughout the body and is involved in the regulation of many important cellular processes that are critical for the development and maintenance of tissues. It is a key regulator of the TGF-β signaling pathway and is involved in the regulation of cell proliferation, cell differentiation, and cell-cell adhesion. OSM is a potential drug target for several diseases due to its involvement in the regulation of these processes, including cancer, autoimmune diseases, and diseases of the gastrointestinal tract. Further research is needed to fully understand the role of OSM as a drug target and to develop effective treatments for these diseases.

Protein Name: Oncostatin M

Functions: Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIFR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST). Involved in the maturation of fetal hepatocytes, thereby promoting liver development and regeneration (By similarity)

The "OSM Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OSM comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OSMR | OSMR-DT | OSR1 | OSR2 | OST4 | OSTC | OSTCP1 | OSTF1 | OSTF1P1 | OSTM1 | OSTM1-AS1 | OSTN | OSTN-AS1 | OTC | OTOA | OTOAP1 | OTOF | OTOG | OTOGL | OTOL1 | OTOP1 | OTOP2 | OTOP3 | OTOR | OTOS | OTP | OTUB1 | OTUB2 | OTUD1 | OTUD3 | OTUD4 | OTUD5 | OTUD6A | OTUD6B | OTUD6B-AS1 | OTUD7A | OTUD7B | OTULIN | OTULINL | OTX1 | OTX2 | OTX2-AS1 | OVAAL | OVCA2 | OVCH1 | OVCH1-AS1 | OVCH2 | OVGP1 | OVOL1 | OVOL1-AS1 | OVOL2 | OVOL3 | OVOS2 | OXA1L | OXA1L-DT | OXCT1 | OXCT1-AS1 | OXCT2 | OXCT2P1 | OXER1 | OXGR1 | OXLD1 | OXNAD1 | OXR1 | OXSM | OXSR1 | OXT | OXTR | Oxysterol-binding protein | Oxysterols receptor LXR | P2RX1 | P2RX2 | P2RX3 | P2RX4 | P2RX5 | P2RX5-TAX1BP3 | P2RX6 | P2RX6P | P2RX7 | P2RY1 | P2RY10 | P2RY10BP | P2RY11 | P2RY12 | P2RY13 | P2RY14 | P2RY2 | P2RY4 | P2RY6 | P2RY8 | P2X Receptor | P2Y purinoceptor | P3H1 | P3H2 | P3H3 | P3H4 | P3R3URF-PIK3R3 | P4HA1 | P4HA2 | P4HA3