Target Name: OVCA2
NCBI ID: G124641
Review Report on OVCA2 Target / Biomarker Content of Review Report on OVCA2 Target / Biomarker
OVCA2
Other Name(s): ovarian cancer-associated gene 2 protein | OVCA2_HUMAN | ovarian tumor suppressor candidate 2 | Candidate tumor suppressor in ovarian cancer 2 | Esterase OVCA2 | Ovarian cancer gene-2 protein | ovarian cancer gene-2 protein | OVCA2 serine hydrolase domain containing | candidate tumor suppressor in ovarian cancer 2

OVCA2: The Potential Drug Target for Ovarian Cancer

Ovarian cancer is a leading cause of cancer death in women, with estimated cases reaching over 21,000 per year in the United States alone. Despite advances in treatment, the survival rate for ovarian cancer remains relatively stagnant, with a five-year survival rate of only 40%. The discovery of new biomarkers and drug targets has the potential to significantly improve the treatment outcomes for ovarian cancer patients. One such potential drug target is OVCA2, a gene associated with ovarian cancer in women.

OVCA2: The Ovarian Cancer-Associated Gene 2 Protein

OVCA2 is a gene that has been identified as a potential drug target for ovarian cancer. The gene was first identified in 2006 and is located on the X chromosome. OVCA2 is a protein that is expressed in a variety of tissues, including breast tissue, and has been shown to be involved in the development and progression of ovarian cancer.

Studies have shown that high levels of OVCA2 are associated with poor prognosis in ovarian cancer patients. In addition, women with ovarian cancer who have high levels of OVCA2 may also have an increased risk of recurrence. These findings suggest that targeting OVCA2 may be a promising strategy for the treatment of ovarian cancer.

OVCA2 as a Drug Target

The potential drug target for OVCA2 is based on its involvement in the development and progression of ovarian cancer. OVCA2 has been shown to promote the growth and survival of ovarian cancer cells, and it is possible that targeting OVCA2 may inhibit the growth of these cancer cells.

One potential approach to targeting OVCA2 is to use a drug that inhibits its activity. This could be done through a variety of mechanisms, such as blocking the interaction between OVCA2 and other proteins, or by inhibiting the activity of OVCA2 itself.

Another potential approach to targeting OVCA2 is to use a drug that activates its downregulation. OVCA2 has been shown to be expressed in a variety of tissues and has been shown to be involved in the regulation of cell growth and differentiation. By activating OVCA2's downregulation, it may be possible to induce the growth and proliferation of ovarian cancer cells.

OVCA2 as a Biomarker

In addition to its potential as a drug target, OVCA2 may also be a useful biomarker for the diagnosis and prognosis of ovarian cancer. The expression of OVCA2 has been shown to be associated with poor prognosis in ovarian cancer patients, and high levels of OVCA2 have been shown to be associated with poor outcomes in ovarian cancer clinical trials.

The potential use of OVCA2 as a biomarker for ovarian cancer has implications for the development of new diagnostic tests and therapies. By detecting high levels of OVCA2 in cancer cells or in the circulation, diagnostic tests that can accurately detect OVCA2 expression may be developed, which could help to improve the accuracy of cancer diagnosis.

In addition, the use of OVCA2 as a biomarker for ovarian cancer could also be used to evaluate the effectiveness of different treatments. For example, by measuring the levels of OVCA2 in cancer cells or in the circulation before and after treatment, it may be possible to determine whether treatment is effective in reducing OVCA2 expression and improving cancer outcomes.

OVCA2 as a Potential Drug Target and Biomarker

In conclusion, OVCA2 is a gene that has been identified as a potential drug target for ovarian cancer. The evidence suggests that targeting OVCA2 may be a promising strategy for the treatment of ovarian cancer. Additionally, OVCA2 may also be a useful biomarker for the diagnosis and prognosis of ovarian cancer. Further research is needed to determine the effectiveness of OVCA2 as a drug target and biomarker in the treatment of ovarian cancer.

Protein Name: OVCA2 Serine Hydrolase Domain Containing

The "OVCA2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OVCA2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

OVCH1 | OVCH1-AS1 | OVCH2 | OVGP1 | OVOL1 | OVOL1-AS1 | OVOL2 | OVOL3 | OVOS2 | OXA1L | OXA1L-DT | OXCT1 | OXCT1-AS1 | OXCT2 | OXCT2P1 | OXER1 | OXGR1 | OXLD1 | OXNAD1 | OXR1 | OXSM | OXSR1 | OXT | OXTR | Oxysterol-binding protein | Oxysterols receptor LXR | P2RX1 | P2RX2 | P2RX3 | P2RX4 | P2RX5 | P2RX5-TAX1BP3 | P2RX6 | P2RX6P | P2RX7 | P2RY1 | P2RY10 | P2RY10BP | P2RY11 | P2RY12 | P2RY13 | P2RY14 | P2RY2 | P2RY4 | P2RY6 | P2RY8 | P2X Receptor | P2Y purinoceptor | P3H1 | P3H2 | P3H3 | P3H4 | P3R3URF-PIK3R3 | P4HA1 | P4HA2 | P4HA3 | P4HB | P4HTM | PA28 Complex | PA28gamma Complex | PA2G4 | PA2G4P1 | PA2G4P4 | PAAF1 | PABIR1 | PABIR2 | PABIR3 | PABP-dependent poly(A) nuclease (PAN) complex | PABPC1 | PABPC1L | PABPC1L2A | PABPC1L2B | PABPC1P10 | PABPC1P2 | PABPC1P4 | PABPC1P7 | PABPC3 | PABPC4 | PABPC4-AS1 | PABPC4L | PABPC5 | PABPN1 | PABPN1L | PACC1 | PACERR | PACRG | PACRG-AS2 | PACRGL | PACS1 | PACS2 | PACSIN1 | PACSIN2 | PACSIN3 | PADI1 | PADI2 | PADI3 | PADI4 | PADI6 | PAEP | PAEPP1