OXCT2: A Potential Drug Target for Androgene-Driven Conditions

Target Name: OXCT2

NCBI ID: G64064

OXCT2

OXCT2: A Potential Drug Target for Androgene-Driven Conditions

OXCT2 (Testis-Specific Succinyl-CoA:3-Oxoacid CoA-Transferase) is a protein that plays a crucial role in the regulation of testosterone levels in the body. It is a key enzyme in the succinyl-coenzyme A (SCA) cycle, which is a central metabolic pathway that generates testosterone. OXCT2 is responsible for transporting the carbonate group from the 3-oxoacid CoA precursor to the 3-oxoacid CoA product in the SCA cycle.

The SCA cycle is a critical pathway for the production of testosterone, which is a primary androgene in males. The testis is the primary site of testosterone production, and the SCA cycle is responsible for generating the majority of the testosterone produced by the testis. OXCT2 is a key enzyme in this cycle, and its function is to transport the carbonate group from the 3-oxoacid CoA precursor to the 3-oxoacid CoA product.

In addition to its role in the SCA cycle, OXCT2 has also been shown to play a role in the regulation of other cellular processes. For example, it has been shown to be involved in the regulation of cell death, and has been shown to play a role in the development of cancer.

Given its role in the SCA cycle and its potential involvement in other cellular processes, OXCT2 is an attractive drug target for researchers. Many studies have investigated the effects of drugs that interact with OXCT2, with some showing promise for treating a variety of conditions.

One of the most promising areas of research is the use of OXCT2 as a drug target for treating androgene-dependent conditions, such as prostate cancer and androgen-induced aggression in women. Studies have shown that OXCT2 is involved in the production of androgens, and that inhibiting its function may be an effective way to treat these conditions.

Another promising area of research is the use of OXCT2 as a biomarker for tracking the effectiveness of androgens. Many androgens, including testosterone, have been shown to have a negative impact on the growth and survival of cancer cells. By using OXCT2 as a biomarker for androgens, researchers may be able to monitor the effectiveness of androgens in cancer treatment.

In conclusion, OXCT2 is a protein that plays a crucial role in the regulation of testosterone levels in the body. Its function as a key enzyme in the SCA cycle makes it an attractive drug target for researchers, and its potential involvement in other cellular processes makes it a promising biomarker for tracking the effectiveness of androgens. Further research is needed to fully understand the role of OXCT2 in the regulation of testosterone and its potential as a drug and biomarker.

Protein Name: 3-oxoacid CoA-transferase 2

Functions: Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity)

The "OXCT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about OXCT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets