AURKAIP1: A Potential Drug Target and Biomarker for Aurora-A Kinase Interaction

Target Name: AURKAIP1

NCBI ID: G54998

AURKAIP1

AURKAIP1: A Potential Drug Target and Biomarker for Aurora-A Kinase Interaction

Aurora-A kinase (Aurora-A) is a key enzyme involved in the control of cell proliferation and survival. The Aurora-A kinase is a protein that plays a crucial role in regulating cell cycle progression and apoptosis. It is composed of four subunits: A, B, C, and D. Aurora-A kinase is an essential protein for cell growth and development, and it is involved in many cellular processes, including cell division, apoptosis, and cell survival.

AURKAIP1 is a protein that interacts with Aurora-A kinase. It is a 21-kDa protein that is composed of 124 amino acid residues. AURKAIP1 is primarily localized to the endoplasmic reticulum (ER) and cytoplasm. It has been shown to interact with Aurora-A kinase, and this interaction is important for the function of Aurora-A kinase.

AURKAIP1 has been shown to play a critical role in the regulation of cell cycle progression and apoptosis. It is involved in the regulation of Aurora-A kinase activity, and it has been shown to inhibit the activity of Aurora-A kinase. This means that when Aurora-A kinase is activated, AURKAIP1 is able to inhibit its activity, thereby regulating cell cycle progression and apoptosis.

AURKAIP1 has also been shown to play a role in the regulation of cell survival. It is involved in the regulation of cell survival by controlling the apoptosis-associated protein (AP-1) expression. AP-1 is a protein that is involved in cell apoptosis, and it is composed of 41 amino acid residues. AURKAIP1 has been shown to interact with AP-1 and to regulate its expression. This means that when Aurora-A kinase is activated, AURKAIP1 is able to regulate the expression of AP-1, thereby controlling cell survival.

AURKAIP1 has been shown to play a critical role in the regulation of cellular processes, including cell growth, apoptosis, and cell survival. It is involved in the regulation of Aurora-A kinase activity, and it has been shown to inhibit the activity of Aurora-A kinase. This means that when Aurora-A kinase is activated, AURKAIP1 is able to inhibit its activity, thereby regulating cell cycle progression and apoptosis.

In conclusion, AURKAIP1 is a protein that interacts with Aurora-A kinase. It is a critical protein that plays a role in the regulation of cell cycle progression, apoptosis, and cell survival. AURKAIP1 has been shown to inhibit the activity of Aurora-A kinase, and this interaction is important for the function of Aurora-A kinase. Therefore, AURKAIP1 may be a potential drug target and biomarker for Aurora-A kinase interaction.

Protein Name: Aurora Kinase A Interacting Protein 1

Functions: May act as a negative regulator of Aurora-A kinase, by down-regulation through proteasome-dependent degradation

The "AURKAIP1 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about AURKAIP1 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
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•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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