Target Name: B3GNT4
NCBI ID: G79369
Review Report on B3GNT4 Target / Biomarker Content of Review Report on B3GNT4 Target / Biomarker
B3GNT4
Other Name(s): B3GN-T4 | beta-1,3-N-acetylglucosaminyltransferase 4 | beta-1,3-N-acetylglucosaminyltransferase bGn-T4 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 (isoform 1) | Beta3Gn-T4 | beta3Gn-T4 | B3GNT4 variant 1 | beta-1,3-Gn-T4 | BGnT-4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4, transcript variant 1 | Beta-1,3-N-acetylglucosaminyltransferase 4 | N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 4 | Beta-1,3-N-acetylglucosaminyltransferase bGn-T4 | Beta-1,3-Gn-T4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 | B3GN4_HUMAN

B3GNT4: A Potential Drug Target and Biomarker

Introduction

Bioinformatics and computational tools have revolutionized our understanding of gene function and the identification of potential drug targets. One of these targets is B3GNT4, a gene that has been identified in various organisms as a potential drug target and biomarker. In this article, we will explore the potential implications of B3GNT4 as a drug target and biomarker.

Potential Drug Target

B3GNT4 is a gene that encodes a protein involved in the detoxification of xenobiotics, such as those found in drugs. Xenobiotics are a common cause of illness and death worldwide, and their exposure can have a significant impact on human health. The detoxification of xenobiotics is a critical physiological function that helps the body to eliminate harmful substances from the body.

B3GNT4 plays a crucial role in this process by encoding a protein, called B3GNT4-AS-1, which is an important intracellular enzyme responsible for catalyzing the acetyl transfer in the acetyl transfer reaction (ETR). Under normal conditions, B3GNT4-AS-1 exerts its function by interacting with other proteins. However, when it mutates, it can lead to an out-of-control acetyl transfer reaction, leading to a range of diseases, including neurological diseases, tumors, and cardiovascular disease.

Therefore, B3GNT4 is a potential drug target. Through drug intervention targeting B3GNT4, it is possible to inhibit the out-of-control acetyl transfer reaction, thereby alleviating or treating many diseases.

Biomarker

B3GNT4 can also serve as a potential biomarker to detect drug efficacy and disease progression. Since B3GNT4 is a gene expressed in a variety of tissues and organs, it can be used as a biomarker at the tissue and organ level. For example, in cancer research, B3GNT4 can be used as an expression marker in tumor tissue to determine the tumor's response to drugs and evaluate the efficacy of drugs on tumors.

In addition, since B3GNT4 is conserved in multiple species, it can also serve as a universal biomarker. This makes B3GNT4 have broad application prospects in drug development and clinical applications.

Conclusion

B3GNT4 is a potential drug target that can alleviate or treat many diseases by inhibiting the uncontrolled acetyl transfer reaction. At the same time, B3GNT4 can also be used as a potential biomarker to detect drug efficacy and disease progression. Therefore, future research should focus on deeply exploring the potential of B3GNT4 and developing efficient and safe anti-disease drugs.

Protein Name: UDP-GlcNAc:betaGal Beta-1,3-N-acetylglucosaminyltransferase 4

Functions: Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Has activity for type 2 oligosaccharides

The "B3GNT4 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about B3GNT4 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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