Target Name: B3GNT9
NCBI ID: G84752
Review Report on B3GNT9 Target / Biomarker Content of Review Report on B3GNT9 Target / Biomarker
B3GNT9
Other Name(s): Beta3Gn-T9 | beta-1,3-Gn-T9 | beta3Gn-T9 | Beta-1,3-N-acetylglucosaminyltransferase 9 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9 | beta-1,3-N-acetylglucosaminyltransferase 9 | BGnT-9 | B3GN9_HUMAN | Beta-1,3-Gn-T9 | Beta-1,3-galactosyltransferase-related protein | beta-1,3-galactosyltransferase-related protein

B3GNT9: A Potential Drug Target and Biomarker

The identification of potential drug targets is a critical step in the development of new treatments for various diseases. One promising approach is to target specific proteins that are involved in disease progression. One such protein is B3GNT9, which has been identified as a potential drug target and biomarker for various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Beta3Gn-T9: Structure and Function

Beta3Gn-T9 is a protein that is expressed in many different tissues, including the brain, pancreas, and gastrointestinal tract. It is a 21-kDa protein that consists of two distinct domains: a N-terminal transmembrane domain and a C-terminal cytoplasmic domain. The N-terminal domain contains a unique farnesylated cysteine residue, which is important for the protein's stability and localization to the endoplasmic reticulum. The C-terminal domain contains a single glycophosphorylated residue, which is involved in the protein's interaction with other cellular structures.

Beta3Gn-T9 plays a crucial role in various physiological processes, including cell signaling, metabolism, and inflammation. It is involved in the regulation of cellular processes that are essential for the survival of cells, including cell adhesion, migration, and apoptosis. Beta3Gn-T9 is also involved in the regulation of metabolism, including the transport of nutrients into the cell and the detoxification of harmful substances. In addition, it is involved in the regulation of inflammation, including the regulation of immune cell function and the modulation of inflammation.

Drug Targeting and Biomarker Potential

The potential drug targeting of B3Gnt9 is based on its involvement in various cellular processes that are essential for the survival of cells. One of the potential drug targets for B3Gnt9 is its role in cell adhesion and migration. Beta3Gn-T9 has been shown to play a crucial role in the regulation of cell adhesion and migration, and it is involved in the formation of tight junctions and cadherins, which are essential for the maintenance of cell-cell junctions and the regulation of cell migration. Therefore, drugs that can inhibit the function of Beta3Gn-T9 may be effective in treating various diseases, including cancer, neurodegenerative diseases, and autoimmune disorders.

Another potential drug target for B3Gnt9 is its role in the regulation of metabolism. Beta3Gn-T9 is involved in the regulation of cellular metabolism, including the transport of nutrients into the cell and the detoxification of harmful substances. Therefore, drugs that can inhibit the function of Beta3Gn-T9 may be effective in treating various diseases, including obesity, diabetes, and neurodegenerative diseases.

In addition, B3Gnt9 is also involved in the regulation of inflammation, including the regulation of immune cell function and the modulation of inflammation. Therefore, drugs that can inhibit the function of Beta3Gn-T9 may be effective in treating various inflammatory diseases, including cancer, autoimmune disorders, and neurodegenerative diseases.

Current Research and Theoretical Context

While the potential drug targeting of B3Gnt9 is an exciting area of research, there is still much to be learned about its function and the molecular mechanisms that regulate its activity. Currently, there are several studies that have investigated the function of B3Gnt9 in various cellular processes, including its role in cell adhesion, migration, and metabolism. These studies have provided valuable information about the molecular mechanisms that regulate B3Gnt9's activity and its potential as a drug target.

In addition, there are also several theoretical models that have been proposed to explain the function

Protein Name: UDP-GlcNAc:betaGal Beta-1,3-N-acetylglucosaminyltransferase 9

The "B3GNT9 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about B3GNT9 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

More Common Targets

B3GNTL1 | B4GALNT1 | B4GALNT2 | B4GALNT3 | B4GALNT4 | B4GALT1 | B4GALT2 | B4GALT3 | B4GALT4 | B4GALT5 | B4GALT6 | B4GALT7 | B4GAT1 | B4GAT1-DT | B7 antigen | B9D1 | B9D2 | BAALC | BAALC-AS1 | BAALC-AS2 | BAAT | BABAM1 | BABAM2 | BABAM2-AS1 | BACE1 | BACE1-AS | BACE2 | BACH1 | BACH2 | BAD | BAG1 | BAG2 | BAG3 | BAG4 | BAG5 | BAG6 | BAGE | BAGE2 | BAGE3 | BAGE4 | BAGE5 | BAHCC1 | BAHD1 | BAIAP2 | BAIAP2-DT | BAIAP2L1 | BAIAP2L2 | BAIAP3 | BAK1 | BALR6 | BAMBI | BANCR | BANF1 | BANF2 | BANK1 | BANP | BAP1 | BARD1 | BARHL1 | BARHL2 | BARX1 | BARX1-DT | BARX2 | BASC complex | BASP1 | BASP1-AS1 | BASP1P1 | BATF | BATF2 | BATF3 | BAX | BAZ1A | BAZ1A-AS1 | BAZ1B | BAZ2A | BAZ2B | BAZ2B-AS1 | BBC3 | BBIP1 | BBLN | BBOF1 | BBOX1 | BBOX1-AS1 | BBS1 | BBS10 | BBS12 | BBS2 | BBS4 | BBS5 | BBS7 | BBS9 | BBSome complex | BBX | BCAM | BCAN | BCAN-AS1 | BCAP29 | BCAP31 | BCAR1 | BCAR3