Target Name: B4GALT2
NCBI ID: G8704
Review Report on B4GALT2 Target / Biomarker Content of Review Report on B4GALT2 Target / Biomarker
B4GALT2
Other Name(s): B4GT2_HUMAN | Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase | UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 2 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 2 | Beta4Gal-T2 | Beta-1,4-GalTase 2 | b4Gal-T2 | Beta-1,4-galactosyltransferase 2 (isoform a) | B4Gal-T2 | UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 2 | Beta-1,4-galactosyltransferase 2, transcript variant 2 | beta4Gal-T2 | nal synthase | Beta-4-GalT2 | beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2 | B4GALT2 variant 1 | beta-1,4-galactosyltransferase 2 | Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase | beta-1,4-GalTase 2 | lactose synthase A protein | B4Gal-T3 | beta-4-GalT2 | UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 2 | Nal synthase | N-acetyllactosamine synthase | Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 2 | B4GALT2 variant 2 | Beta-1,4-galactosyltransferase 2 | Beta-1,4-galactosyltransferase 2 (isoform b) | Beta-1,4-galactosyltransferase 2, transcript variant 1 | Lactose synthase A protein | beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase

B4GALT2: A Potential Drug Target for Cancer

B4GALT2 (B4GT2_HUMAN), a gene located on chromosome 6p21.2, has been identified as a potential drug target and biomarker for various diseases, including cancer. Its function and role in human biology have been extensively studied, and its potential as a drug target continue to grow.

B4GALT2 is a non-coding RNA molecule that is expressed in various tissues and cells of the body. It is a part of the B4GALT gene family, which is known for its role in cell signaling and metabolism. The B4GALT2 gene has four exons, and its protein product has a molecular weight of approximately 18 kDa.

B4GALT2 has been shown to play a significant role in various cellular processes, including cell adhesion, migration, and invasion. It is a critical regulator of theNotch signaling pathway, a well-established pathway that regulates cell proliferation, differentiation, and survival. TheNotch signaling pathway is involved in the development and maintenance of tissues and organs, and B4GALT2 has been shown to be involved in the regulation of cell proliferation, differentiation, and survival.

In addition to its role in cell signaling, B4GALT2 has also been shown to play a significant role in the development and progression of various diseases, including cancer. Its expression has been observed in various types of cancer, including breast, ovarian, and prostate cancers. B4GALT2 has also been shown to be involved in the regulation of the angiogenic factors, which are responsible for the formation of new blood vessels that contribute to tumor growth.

The potential implications of B4GALT2 as a drug target are significant. Its involvement in the regulation of cell signaling and its role in the development and progression of various diseases make it an attractive target for drug development. Additionally, its small size and the availability of biochemical assays that can be used to measure its expression make it an ideal candidate for use in high-throughput screening experiments.

In conclusion, B4GALT2 is a promising drug target and biomarker for various diseases, including cancer. Its involvement in the regulation of cell signaling and its role in the development and progression of various diseases make it an attractive target for drug development. Further research is needed to fully understand its potential as a drug target and to develop effective therapies that can be used to treat various diseases.

Protein Name: Beta-1,4-galactosyltransferase 2

Functions: Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids (PubMed:9405390). Can produce lactose (PubMed:9405390)

The "B4GALT2 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about B4GALT2 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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