ANTs: Potential Drug Targets for Progressive Ankylosis (G56172)

Target Name: ANKH

NCBI ID: G56172

ANKH

ANTs: Potential Drug Targets for Progressive Ankylosis

ANKH (Progressive ankylosis protein homolog) is a protein that is expressed in a variety of tissues throughout the body, including the skin, bone, and soft tissues. It is a member of the progressive ankylosis protein (PAP) family, which is characterized by the presence of a unique genetic mutation that results in the production of ankylosing spondylitis-like proteins.

One of the unique features of ANKH is its ability to cause progressive ankylosis, a type of joint inflammation that can lead to progressive joint stiffness and reduced mobility. This condition is typically treated with non-steroidal anti-inflammatory drugs (NSAIDs), which can provide relief from symptoms but not a cure.

The ANKH gene has been identified as a potential drug target for the treatment of progressive ankylosis. By targeting the ANKH protein, researchers hope to reduce inflammation and improve joint mobility in patients with this condition.

In addition to its potential as a drug target, ANKH has also been shown to be a potential biomarker for the diagnosis and progression of progressive ankylosis. The presence of ANKH in tissues from patients with progressive ankylosis was identified using a variety of techniques, including immune Histochemistry and Western blotting.

The ANKH protein is also expressed in a variety of tissues that are affected by progressive ankylosis, including the skin, bone, and soft tissues. This makes it a potential biomarker for the condition, as its levels can be easily detected in these tissues.

In conclusion, ANKH is a protein that has the potential to be a drug target for the treatment of progressive ankylosis. Its unique structure and its expression in a variety of tissues make it a promising candidate for research into the underlying causes of this condition. Additionally , ANKH has also been shown to be a potential biomarker for the diagnosis and progression of progressive ankylosis, which could be used for the early detection and monitoring of this condition. Further research is needed to fully understand the role of ANKH in the treatment of progressive ankylosis and its potential as a biomarker.

Protein Name: ANKH Inorganic Pyrophosphate Transport Regulator

Functions: Regulates intra- and extracellular levels of inorganic pyrophosphate (PPi), probably functioning as PPi transporter

The "ANKH Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANKH comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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