Target Name: ANKS3
NCBI ID: G124401
Review Report on ANKS3 Target / Biomarker Content of Review Report on ANKS3 Target / Biomarker
ANKS3
Other Name(s): Ankyrin repeat and SAM domain-containing protein 3 | Ankyrin repeat and SAM domain-containing protein 3 (isoform 1) | ANKS3_HUMAN | ankyrin repeat and SAM domain-containing protein 3 | KIAA1977 | ankyrin repeat and sterile alpha motif domain containing 3 | Ankyrin repeat and sterile alpha motif domain containing 3, transcript variant 1 | ANKS3 variant 1

ANKS3: A Potential Drug Target and Biomarker

Introduction

ANKS3 (Ankyrin repeat and SAM domain-containing protein 3) is a protein that has been identified as a potential drug target and biomarker. It is a member of the ANKYRIN repeat protein family, which is characterized by the presence of a characteristic repeat sequenceANKYRIN repeat. ANKS3 plays important biological functions in cells, such as participating in cell signaling, DNA replication, RNA splicing and other processes. In addition, ANKS3 also plays a role in tumor occurrence and development, such as promoting the proliferation and invasion of tumor cells. Therefore, ANKS3 has become a research subject that has attracted much attention.

drug target

ANKS3 was found to be a high pharmacological target in drug screening. First, ANKS3 has multiple signal transduction pathways at the cellular level, such as PI3K/Akt, MAPK/ERK, FGFR, etc. These signaling pathways play a key role in tumor occurrence and development. At the same time, ANKS3 also has the characteristics of participating in DNA replication, RNA splicing and other processes, which makes it a potential drug target.

In addition, ANKS3 also plays an important role in the invasion and proliferation of tumor cells. Studies have shown that ANKS3 can promote the invasion and metastasis of tumor cells, as well as the proliferation and proliferation of tumor cells. Therefore, ANKS3 has great potential for development as a drug target.

biomarker

ANKS3 can also serve as a potential biomarker to detect tumor development and treatment efficacy. Because ANKS3 is expressed at a high level in tumor cells, it can be used as a tumor biomarker. During tumor diagnosis and treatment, monitoring the expression level of ANKS3 can be used to evaluate treatment effects and predict tumor recurrence.

Structure and function

The protein structure and function of ANKS3 are closely related. ANKS3 is a protein composed of 104 amino acids with a molecular weight of 11.3 kDa. The protein structure of ANKS3 includes an N-terminal 伪-helix, a central 尾-page, and a C-terminal domain. Among them, the N-terminal 伪-helix of ANKS3 consists of 11 amino acids and is the most functionally important part of the ANKS3 molecule.

During the functional study, scientists found that the N-terminal 伪-helix of ANKS3 can interact with a variety of proteins, such as DNA-binding proteins, cytoskeletal proteins, etc. These interactions further enhance the function of ANKS3, making it a potential drug target.

Research status

Currently, research on ANKS3 mainly focuses on drug targets, biomarkers, and its role in tumor occurrence and development. Although certain results have been achieved in the aforementioned aspects, as a complex biomolecule, ANKS3's function and mechanism of action still need to be further studied. Therefore, future research should focus on in-depth study of the molecular mechanism of ANKS3 to better understand its role in tumorigenesis and development and provide a theoretical basis for the development of drugs.

in conclusion

As a protein with multiple biological functions, ANKS3 has a high pharmacological target. At the same time, ANKS3 can also be used as a potential biomarker to detect tumor development and treatment effects. In the future, research should delve into the molecular mechanism of ANKS3 to better understand its role in tumor occurrence and development and provide a theoretical basis for the development of drugs.

Protein Name: Ankyrin Repeat And Sterile Alpha Motif Domain Containing 3

Functions: May be involved in vasopressin signaling in the kidney

The "ANKS3 Target / Biomarker Review Report" is a customizable review of hundreds up to thousends of related scientific research literature by AI technology, covering specific information about ANKS3 comprehensively, including but not limited to:
•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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